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The analysis method of intracranial hypointense disease on T2WI
ZHAO Xuemei  QIAN Yinfeng 

Cite this article as: Zhao XM, Qian YF. The analysis method of intracranial hypointense disease on T2WI[J]. Chin J Magn Reson Imaging, 2021, 12(9): 81-87. DOI:10.12015/issn.1674-8034.2021.09.021.


[Abstract] Most of intracranial lesions have hyperintense on T2WI, but part of the intracranial lesions can be characterized hypointense on T2WI, T2WI hypointense is an important imaging features of this kind of disease. On this basis, we give a induction and summary of these diseases, we hope for clinical work to narrow the differential diagnosis, and even can diagnose some diseases. The types of intracranial T2WI hypointense lesions are complex and the pathological basis is different.In this paper, according to the pathology base can be divided into nine categories, including hemoglobin degradation products (deoxyhemoglobin,intracellular methemoglobin hemoglobin and hemosiderin), containing melanin lesions, rich in mucus/protein/cholesterol clefts, rich in cell lesion, mineral deposits, flowing void effect, intracranial pneumatosis, fiber lesions and coagulation necrosis. The clinical lesion manifestations, pathological features and MRI features of the specific diseases under each category were summarized. The clinical features (such as age, sex, clinical manifestations and laboratory examination) and MRI manifestations (including lesion location, morphology, adjacent structure, and peripheral edema, etc.) that have diagnostic and differential diagnostic significance were emphasized. However, it is sometimes difficult to make a definitive diagnosis based on the low signal of T2WI alone. Therefore, the typical features of these diseases in other sequences and enhanced T1WI are also described. Combined with clinical and other MRI sequences, it is helpful for the diagnosis and differential diagnosis of T2WI hypointense lesions. A variety of intracranial lesions may present as T2WI hypointensity, but each of them has its own characteristics. We summarize their imaging findings for diagnosis.
[Keywords] brain；magnetic resonance imaging；T2 weighted imaging；hypointense；diagnose；differential diagnosis；lecture

ZHAO Xuemei   QIAN Yinfeng*  

Department of Radiology, the First Affiliated Hospital of Anhui Medical University, Hefei 230022, China

QianYF, E-mail: 894206876@qq.com

Conflicts of interest   None.

Received  2021-04-15
Accepted  2021-06-11
DOI: 10.12015/issn.1674-8034.2021.09.021
Cite this article as: Zhao XM, Qian YF. The analysis method of intracranial hypointense disease on T2WI[J]. Chin J Magn Reson Imaging, 2021, 12(9): 81-87. DOI:10.12015/issn.1674-8034.2021.09.021.

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