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• Clinical Article •
The value of enhanced T2 star weighted angiography in the diagnosis of cervical cancer and the evaluation of radiotherapy effect
WANG Yanming  YIN Cheng  ZHOU Tao  HAN Yu  GAO Shanshan  GUAN Yue  WANG Xizhen 

Cite this article as: Wang YM, Yin C, Zhou T, et al. The value of enhanced T2 star weighted angiography in the diagnosis of cervical cancer and the evaluation of radiotherapy effect[J]. Chin J Magn Reson Imaging, 2021, 12(10): 22-25, 31. DOI:10.12015/issn.1674-8034.2021.10.005.


[Abstract] Objective To analyze the characteristics of enhanced T2 star-weighted angiography (ESWAN) before and after radiotherapy for normal cervical myometrium and cervical cancer, and to explore the value of ESWAN in cervical cancer diagnosis and radiotherapy efficacy. Materials andMethods Thirty-five patients with cervical cancer confirmed by pathology, thirty-two normal female volunteers of the same age, and fifteen patients with cervical cancer received radiotherapy. Routine pelvic MRI and ESWAN examinations were performed before and after cervical cancer treatment and in volunteers. ESWAN parameter values were measured between the lesion area and normal cervical myometrium, and before and after radiotherapy. The differences in ESWAN parameters between cervical cancer and normal cervical myometrium were compared and analyzed. Different parameters of ESWAN were evaluated the effect of radiotherapy.Results The magnitude value, phase value, R2* value and T2* value of cervical cancer and normal cervical myometrium were (1237.25±472.50) and (1638.72±406.70), (-0.053±0.072) and (0.025±0.201), (30.89±10.18) and (25.48±7.34), (36.19±10.25) and (40.38±8.26). The magnitude value, phase value, R2* value and T2* value of 15 patients with cervical cancer before and after radiotherapy were (1198.28±210.58) and (817.33±131.11), (-0.144±0.191) and (-0.011±0.083), (36.01±10.78) and (26.86±8.58), (31.54±6.28) and (40.46±7.69). The magnitude value, phase value and T2* value of cervical cancer were lower than normal cervical myometrium, and the R2* value increased, and the difference was statistically significant (P＜0.05). After radiotherapy, the magnitude value and R2* value decreased, while the phase value and T2* value increased, and the difference was statistically significant (P＜0.05).Conclusion The ESWAN parameters have certain value in the diagnosis of cervical cancer. At the same time, by analyzing the changes of different ESWAN parameter values before and after radiotherapy, the histological changes of cervical cancer after radiotherapy can be evaluated to a certain extent.
[Keywords] cervical cancer；enhanced T2 star weighted angiography；susceptibility weighted imaging；magnetic resonance imaging；radiotherapy

WANG Yanming1   YIN Cheng1   ZHOU Tao1   HAN Yu2   GAO Shanshan2   GUAN Yue2   WANG Xizhen2*  

1 School of Medical Imaging, Weifang Medical University, Weifang 261053, China

2 Imaging Center of Affiliated Hospital of Weifang Medical University, Weifang 261053, China

Wang XZ, E-mail: wangxizhen@wfmc.edu.cn

Conflicts of interest   None.

ACKNOWLEDGMENTS Natural Science Foundation of Shandong Province (No. ZR2017MH037); Shandong Medical and Health Science and Technology Development Plan (No. 2017WS579); Shandong University Scientific Research Plan Project (Science and Technongy) (No. J18KA288).
Received  2021-04-21
Accepted  2021-07-01
DOI: 10.12015/issn.1674-8034.2021.10.005
Cite this article as: Wang YM, Yin C, Zhou T, et al. The value of enhanced T2 star weighted angiography in the diagnosis of cervical cancer and the evaluation of radiotherapy effect[J]. Chin J Magn Reson Imaging, 2021, 12(10): 22-25, 31. DOI:10.12015/issn.1674-8034.2021.10.005.

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