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Application value of intraoperative awakening combined with magnetic resonance neuronavigation system in brain tumor surgery in functional area
GAO Hongxia  CHEN Xiaoqin 

Cite this article as: Gao HX, Chen XQ. Application value of intraoperative awakening combined with magnetic resonance neuronavigation system in brain tumor surgery in functional area[J]. Chin J Magn Reson Imaging, 2021, 12(10): 41-44. DOI:10.12015/issn.1674-8034.2021.10.009.


[Abstract] Objective To investigate the value of intraoperative wakefulness combined with MR neuronavigation system in the operation of functional brain tumors. Materials andMethods A total of 50 patients admitted to the department of neurosurgery of our hospital from July 2018 to July 2020 who received surgical treatment for brain tumors in functional areas were selected as the research subjects. They were divided into a control group (25 cases) and an observation group (25 cases) according to the random number table. The observation group was treated with intraoperative awakening combined with magnetic resonance neuronavigation, while the control group was only subjected to magnetic resonance neuronavigation before surgery. All the 50 patients underwent preoperative brain tissue image acquisition by MRI, especially through the diffusion tensor imaging (DTI) sequence and blood oxygenation level dependent functional MRI (BOLD-fMRI) sequence scanning to display the functional areas and reconstruct the corticospinal tract. Three-dimensional imaging models of intracranial structure, tumor structure and surrounding tissue structure were established by using the neuronavigation system. At the same time, patients in the observation group were resected after redefining the functional area by intraoperative wake-up technique. The operative time, tumor resection degree, neurological function (Karnofsky) score and incidence of postoperative complications in 2 groups were observed.Results The operation time and postoperative hospital stay of patients in the observation group were significantly lower than those in the control group (t=-2.232, -5.788, P=0.030, P＜0.001). The tumor resection degree of patients in the observation group was significantly higher than that in the control group (Z=5.128, P=0.028); the KPS score of the observation group six months after surgery was significantly higher than that of the control group (t=4.861, P＜0.001), and the incidence of postoperative complications was significantly lower than that of the control group. The differences were statistically significant (χ2=5.094, P=0.024).Conclusion Intraperitoneal arousal combined with magnetic resonance neuronavigation system can not only improve the maximum degree of tumor resection in the brain functional areas, but also protect the important nerve function in the brain functional areas, which can be popularized in clinical application.
[Keywords] functional brain tumor；intraoperative arousal；magnetic resonance neuronavigation system；diffusion tensor imaging；blood oxygenation level dependent

GAO Hongxia1   CHEN Xiaoqin2*  

1 Anesthesiology Surgery Center, Sichuan People's Hospital of Sichuan Provincial Academy of Medical Sciences, Chengdu 610000

2 Department of Neurosurgery, Sichuan People's Hospital of Sichuan Provincial Academy of Medical Sciences, Chengdu 610000

Chen XQ, E-mail: 710702520@qq.com

Conflicts of interest   None.

Received  2021-05-08
Accepted  2021-08-19
DOI: 10.12015/issn.1674-8034.2021.10.009
Cite this article as: Gao HX, Chen XQ. Application value of intraoperative awakening combined with magnetic resonance neuronavigation system in brain tumor surgery in functional area[J]. Chin J Magn Reson Imaging, 2021, 12(10): 41-44. DOI:10.12015/issn.1674-8034.2021.10.009.

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