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Magnetic resonance research progress in amnestic mild cognitive impairment
LI Xiaoling  CAI Lina  CUI Xuan  PENG Cailiang  MA Cuisong  LIU Shiping  YANG Xu  SUN Xuchen  YUAN Yuan 

Cite this article as: Li XL, Cai LN, Cui X, et al. Magnetic resonance research progress in amnestic mild cognitive impairment[J]. Chin J Magn Reson Imaging, 2021, 12(11): 94-96. DOI:10.12015/issn.1674-8034.2021.11.023.


[Abstract] Alzheimer disease (AD) is a progressive age-related neurodegenerative disease. Mild cognitive impairment (MCI) is a transitional stage between the normal aging process and AD. It is divided into amnestic MCI (aMCI) and non-amnestic MCI. The former is mainly memory impairment, which is considered to be the early stage of AD. The clinical subtypes of aMCI include single-domain (SD) and multi-domain (MD). Different subtypes have different possibilities to progress to AD. At present, the etiology and pathogenesis of AD are unclear, and there is no effective cure. Therefore, early diagnosis, intervention and treatment of aMCI and delay its progression to AD are of great significance. In recent years, magnetic resonance imaging combined with different analysis methods have been applied to the study of aMCI mechanism, which can objectively and indirectly reflect the abnormality of brain structure and functional activity, and provide certain clues for explaining its mechanism. Therefore, this article reviews the progress of aMCI magnetic resonance imaging studies.
[Keywords] structural magnetic resonance imaging；functional magnetic resonance imaging；amnestic mild cognitive impairment；Alzheimer disease

LI Xiaoling1   CAI Lina2   CUI Xuan2   PENG Cailiang1, 2*   MA Cuisong2   LIU Shiping2   YANG Xu2   SUN Xuchen2   YUAN Yuan2  

1 Department of CT and MRI, the First Affiliated Hospital of Heilongjiang University of Traditional Chinese Medicine, Harbin 150040, China

2 Graduate School of Heilongjiang University of traditional Chinese Medicine, Harbin 150040, China

Peng CL, E-mail: 419585226@qq.com

Conflicts of interest   None.

ACKNOWLEDGMENTS This article is supported by the National Natural Science Foundation of China (No. 81973930, 82074537). Heilongjiang Natural Science Foundation of China (No. LH2020H103, H2016081). Harbin Science and Technology Outstanding Discipline Leader Project (No. 2016RAXYJ096). Research Fund of Heilongjiang University of Traditional Chinese Medicine (No. 2019MS03).
Received  2021-06-29
Accepted  2021-09-08
DOI: 10.12015/issn.1674-8034.2021.11.023
Cite this article as: Li XL, Cai LN, Cui X, et al. Magnetic resonance research progress in amnestic mild cognitive impairment[J]. Chin J Magn Reson Imaging, 2021, 12(11): 94-96. DOI:10.12015/issn.1674-8034.2021.11.023.

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