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• Clinical Article •
Diagnostic value of ultra-high b-value DWI in peripheral prostate cancer
ZHAO Yingying  ZHANG Dan  SONG Na  WANG Tao  WANG Zhuo  ZHANG Shaoru  YU Jia  CAI Lei  CHEN Zhiqiang 

Cite this article as: Zhao YY, Zhang D, Song N, et al. Diagnostic value of ultra-high b-value DWI in peripheral prostate cancer[J]. Chin J Magn Reson Imaging, 2021, 12(12): 24-28. DOI:10.12015/issn.1674-8034.2021.12.005.


[Abstract] Objective To investigate the diagnostic efficiency of diffusion weighted imaging (DWI) and apparent diffusion coefficient (ADC) maps with high b value (1000 s/mm2) and ultra-high b value (2000 s/mm2) for benign and malignant lesions of peripheral zone prostate. Materials and Methods: The clinical and imaging data of 64 patients who underwent conventional magnetic resonance imaging and ultra-high b-value DWI imaging of the prostate in the Department of Radiology, General Hospital of Ningxia Medical University from January 2015 to May 2016 were retrospectively analyzed. The images were evaluated by two physicians on T2WI and DWI using a five-point scale based on prostate imaging reporting and data system version 2.0 (PI-RADS V2) and in a double-blind fashion; the lesions were delineated layer by layer on DWI using three-dimensional region of interest (VOI) and the histogram analysis was performed on the ADC values.Results (1) For the diagnosis of prostate cancer, the sensitivity of DWI image obtained by ultra-high b value (2000 s/mm2) was significantly higher than that of high b value (1000 s/mm2) (P＜0.001); (2) Histogram parameter ADC10 had the highest diagnostic efficiency, with the areas under the receiver operating characteristic (ROC) curves of 0.902 [95% CI (0.802—0.962)] and 0.823 [95% CI (0.707—0.907)] respectively (P＞0.05).Conclusions The diagnostic performance of histogram of ADC values corresponding to ultra-high b value and high b value for peripheral zone prostate cancer is similar, while when b value is 2000 s/mm2, the sensitivity of DWI image is higher than 1000 s/mm2. Therefore, ultra-high b-value DWI can help to improve the diagnostic value of peripheral zone prostate cancer.
[Keywords] prostate cancer；magnetic resonance imaging；diagnosis；diffusion weighted imaging；ultra-high b value；histogram analysis

ZHAO Yingying1, 2   ZHANG Dan3   SONG Na3   WANG Tao3   WANG Zhuo3   ZHANG Shaoru3   YU Jia4   CAI Lei1   CHEN Zhiqiang1*  

1 Department of Radiology, General Hospital of Ningxia Medical University, Yinchuan 750004, China

2 Department of Radiology, Fuqing City Hospital Affiliated to Fujian Medical University, Fuqing 350300, China

3 Clinical Medicine School of Ningxia Medical University, Yinchuan 750004, China

4 Department of Genetics, School of Basic Medicine, Ningxia Medical University, Yinchuan 750004, China

Chen ZQ, E-mail: zhiqiang_chen99@163.com

Conflicts of interest   None.

ACKNOWLEDGMENTS Key R&D Plan Project of Ningxia Hui Autonomous Region (No. 2019BEG03033); Ningxia Natural Science Foundation of China (No. 2020AAC03156).
Received  2021-08-16
Accepted  2021-11-05
DOI: 10.12015/issn.1674-8034.2021.12.005
Cite this article as: Zhao YY, Zhang D, Song N, et al. Diagnostic value of ultra-high b-value DWI in peripheral prostate cancer[J]. Chin J Magn Reson Imaging, 2021, 12(12): 24-28. DOI:10.12015/issn.1674-8034.2021.12.005.

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