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Research progress of resting-state functional magnetic resonance imaging in TCM treatment of mild cognitive impairment
LI Xiaoling  CUI Xuan  TONG Xin  CAO Danna  PENG Cailiang  ZHAO Pei  FAN Tingting  LOU Ruizhi  WU Yue 

Cite this article as: Li XL, Cui X, Tong X, et al. Research progress of resting-state functional magnetic resonance imaging in TCM treatment of mild cognitive impairment[J]. Chin J Magn Reson Imaging, 2022, 13(3): 122-125. DOI:10.12015/issn.1674-8034.2022.03.030.


[Abstract] Traditional Chinese medicine (TCM) has made some achievements in the treatment of cognitive impairment, but its therapeutic mechanism is still unclear. Functional magnetic resonance imaging (fMRI) is a commonly used noninvasive in vivo brain function detection technology in the field of brain imaging, and resting-state fMRI (rs-fMRI) is also the preferred method for the study of cognitive disorders. Based on this technology, it is found that the main brain areas related to mild cognitive impairment (MCI) are the frontal lobe, hippocampus and cingulate gyrus. Studies have shown that TCM treatment can regulate the brain function network and neural circuits of MCI. The rs-fMRI technology was used to objectively evaluate the functional connectivity and activity indicators of local brain regions of subjects before and after treatment, to understand the brain effect mechanism of TCM treatment, and to provide new ideas and methods for exploring the therapeutic mechanism of TCM treatment of neurological diseases.
[Keywords] mild cognitive impairment；resting-state functional magnetic resonance imaging；acupuncture；Daoyin exercises；traditional Chinese medicine

LI Xiaoling1   CUI Xuan2   TONG Xin2   CAO Danna1   PENG Cailiang1, 2*   ZHAO Pei2   FAN Tingting2   LOU Ruizhi2   WU Yue2  

1 Department of CT and MRI, the First Hospital Affiliated to Heilongjiang University of Chinese Medicine, Harbin 150040, China

2 Graduate School of Heilongjiang University of Chinese Medicine, Harbin 150040, China

Peng CL, E-mail: p18804618528@163.com

Conflicts of interest   None.

ACKNOWLEDGMENTS National Natural Science Foundation Surface Project of China (No. 82074537, 81373714); Natural Science Foundation of Heilongjiang Province (No. LH2021H101, LH2020H103); Harbin Science and Technology Innovation Talents Outstanding Academic Leader Fund Project (No. 2016RAXYJ096); Harbin Science and Technology Innovation Talent Youth Reserve Fund Project (No. 2017RAQXJ180); Scientific Research Foundation of Heilongjiang University of Traditional Chinese Medicine (No. 2019MS03).
Received  2021-11-10
Accepted  2022-02-17
DOI: 10.12015/issn.1674-8034.2022.03.030
Cite this article as: Li XL, Cui X, Tong X, et al. Research progress of resting-state functional magnetic resonance imaging in TCM treatment of mild cognitive impairment[J]. Chin J Magn Reson Imaging, 2022, 13(3): 122-125. DOI:10.12015/issn.1674-8034.2022.03.030.

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