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Therapeutic effects of radiofrequency ablation for hepatocellular carcinoma: Evaluated by magnetic resonance imaging
MING Zhiqiang  CAO Jinming  CHEN Tianwu  WU Yuping  YANG Liqin  GAO Dan 

Cite this article as: Ming ZQ, Cao JM, Chen TW, et al. Therapeutic effects of radiofrequency ablation for hepatocellular carcinoma: Evaluated by magnetic resonance imaging[J]. Chin J Magn Reson Imaging, 2022, 13(5): 115-119. DOI:10.12015/issn.1674-8034.2022.05.021.


[Abstract] Objective To investigate the feasibility of magnetic resonance imaging (MRI) in evaluating different therapeutic effects of radiofrequency ablation (RFA) for hepatocellular carcinoma (HCC).Materials and Methods From January 2018 to June 2021, 52 HCC patients with a total of 60 lesions treated by RFA from Affiliated Hospital of North Sichuan Medical College underwent MRI plain scan, multiphase enhanced scans, and diffusion weighted imaging (DWI) before the previous treatments and were regularly followed up after this therapy, and the MRI data were retrospectively collected. The sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and accuracy of MRI for detecting complete ablation, tumor residual, local tumor progression and new tumor were statistically calculated.Results (1) For showing complete ablation, the sensitivity, specificity, PPV, NPV and accuracy of MRI were 89.5%, 92.7%, 85.0%, 95.0% and 91.7%, respectively; (2) For detecting tumor residual, the sensitivity, specificity, PPV, NPV and accuracy of MRI were 81.8%, 91.8%, 69.2%, 95.7% and 90.0%, respectively; (3) For demonstrating local tumor progression after RFA, the sensitivity, specificity, PPV, NPV and accuracy of follow-up MRI were 84.6%, 93.2%, 78.6%, 95.3% and 91.2%, respectively; (4) For demonstrating new tumor in liver after RFA, the sensitivity, specificity, PPV, NPV and accuracy of follow-up MRI were 100.0%, 94.7%, 88.9%, 100.0% and 96.3%, respectively.Conclusions When MRI is used to evaluate the efficacy of RFA of HCC, it has a very good potential on the detection of complete ablation, tumor residual, local tumor progression and new tumor in liver, especially of complete ablation and new tumor in liver.
[Keywords] hepatocellular carcinoma；radiofrequency ablation；efficacy evaluation；magnetic resonance imaging；diffusion weighted imaging

MING Zhiqiang1, 2   CAO Jinming3   CHEN Tianwu1*   WU Yuping1   YANG Liqin3   GAO Dan1  

1 Department of Radiology, Affiliated Hospital of North Sichuan Medical College, Sichuan Key Laboratory of Medical Imaging Nanchong 637000, China

2 Department of Radiology, Zigong First People's Hospital, Zigong 643000 China

3 Department of Radiology, Nanchong Central Hospital, Second School of Clinical Medicine, North Sichuan Medical College, Nanchong 637000, China

Chen TW, E-mail: tianwuchen_nsmc@163.com

Conflicts of interest   None.

ACKNOWLEDGMENTS National Natural Science Foundation of China (No. 81050033).
Received  2021-11-08
Accepted  2022-04-22
DOI: 10.12015/issn.1674-8034.2022.05.021
Cite this article as: Ming ZQ, Cao JM, Chen TW, et al. Therapeutic effects of radiofrequency ablation for hepatocellular carcinoma: Evaluated by magnetic resonance imaging[J]. Chin J Magn Reson Imaging, 2022, 13(5): 115-119. DOI:10.12015/issn.1674-8034.2022.05.021.

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