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Research progress of focal cortical dysplasia with FLAIR-negative of magnetic resonance imaging
JU Jingtao  CHEN Nan 

Cite this article as: Ju JT, Chen N. Research progress of focal cortical dysplasia with FLAIR-negative of magnetic resonance imaging[J]. Chin J Magn Reson Imaging, 2022, 13(7): 164-166, 170. DOI:10.12015/issn.1674-8034.2022.07.033.


[Abstract] Focal cortical dysplasia (FCD) is one of the common causes of drug refractory epilepsy. Type Ⅰ accounts for 38.3% of the FCD lesions, while type Ⅱ accounts for 61.7%. Surgery is an effective way for the treatment of FCD. Preoperative detection and accurate localization of the lesions are important factors affecting the mode of operation and prognosis. At present, the diagnosis of FCD mainly depends on MRI. However, up to 40% of type Ⅱ FCD and 85% of type Ⅰ FCD lesions are negative on conventional MRI, which brings great difficulty to diagnosis and operation. With the development of MRI hardware, software and post-processing technology, the negative detection rate of FCD in conventional MRI is greatly improved (overall diagnostic gain rate 31%). Which is great significance for accurate location of lesions, guiding surgery and reducing postoperative seizures. Therefore, this paper reviews the research progress of improving the detection methods of FCD negative on conventional MRI.
[Keywords] magnetic resonance imaging；focal cortical dysplasia；magnetoencephalography；epilepsy；three-dimensional fluid attenuated inversion recover；double inversion recovery sequences；fluid and white matter suppression sequence；fluid and white matter suppression sequence；three-dimensional edge-enhancing gradient echo sequence；voxel-based morphometry；morphometric analysis program；surface-based morphometry；convolutional neural network

JU Jingtao   CHEN Nan*  

Department of Radiology and Nulear Medicine, Xuanwu Hospital, Capital Medical University, Beijing 100053, China

Chen N, E-mail: chenzen8057@sina.com

Conflicts of interest   None.

Received  2021-12-12
Accepted  2022-07-05
DOI: 10.12015/issn.1674-8034.2022.07.033
Cite this article as: Ju JT, Chen N. Research progress of focal cortical dysplasia with FLAIR-negative of magnetic resonance imaging[J]. Chin J Magn Reson Imaging, 2022, 13(7): 164-166, 170. DOI:10.12015/issn.1674-8034.2022.07.033.

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