Research progress of magnetic resonance functional brain imaging in adolescent depression

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DENG Jie HE Jianbo QIU Lihua

Cite this article as: Deng J, He JB, Qiu LH. Research progress of magnetic resonance functional brain imaging in adolescent depression[J]. Chin J Magn Reson Imaging, 2022, 13(8): 101-103, 108. DOI:10.12015/issn.1674-8034.2022.08.022.

Abstract

[Abstract] Due to the high incidence, recurrence and disability rats, adolescent depression has become a common concern of society and clinicians. With the development of imaging technology, functional magnetic resonance imaging (fMRI) has been widely used in the research of adult depression, but few studies on adolescent depression. In recent years, the results of fMRI, magnetic resonance spectroscopy and MR perfusion weighted imaging show that the frontal-limbic system, basal ganglia, corpus callosum, cerebellum and other regions of adolescent depression are abnormal in function, metabolism and blood perfusion. These regions are associated with emotion, memory, reward, cognition and other functions, and may be potential biomarkers of adolescent depression. This paper briefly reviews the research results and potential deficiencies of fMRI in adolescent depression in recent years, in order to provide direction for future research.

[Keywords] adolescent depression；magnetic resonance imaging；magnetic resonance spectroscopy；perfusion weighted imaging；arterial spin labeling；blood oxygenation level dependent

Contributor Information

DENG Jie^{1,
2} HE Jianbo² QIU Lihua^{1,
3*}

¹ Department of Radiology, the Affiliated Hospital of Southwest Medical University, Luzhou 646000, China

² Department of Radiology, the Fourth People's Hospital of Yibin, Yibin 644000, China

³ Neurographic Big Data Research Center, Clinical Research and Translational Center, Second People's Hospital of Yibin City-West China Yibin Hospital, Sichuan University, Yibin 644000, China.

Qiu LH, E-mail: qiulihuah@gmail.com

Conflicts of interest None.

Publication Information

ACKNOWLEDGMENTS Science and Technology Support Program of Sichuan Province (No. 2018JY0666); the 58th batch of Post-doctoral Science Fund of China (No. 2015M582554); Scientific Research Topics of Health and Family Planning Commission of Sichuan Province (No. 150251); Open Project of Sichuan Key Laboratory of Functional and Molecular Imaging (No. SCU-HM-2021001); Project of Health Commission of Yibin City (No. 2020YW085).

Received 2022-02-08

Accepted 2022-07-26

DOI: 10.12015/issn.1674-8034.2022.08.022

Text

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