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Research progress of MRI on myelin oligodendrocyte glycoprotein antibody disease in children
LI Ting  CHEN Xin  WANG Haoru  HE Ling 

Cite this article as: Li T, Chen X, Wang HR, et al. Research progress of MRI on myelin oligodendrocyte glycoprotein antibody disease in children[J]. Chin J Magn Reson Imaging, 2022, 13(9): 123-126. DOI:10.12015/issn.1674-8034.2022.09.029.


[Abstract] Myelin oligodendrocyte glycoprotein antibody disease (MOGAD) is a new subtype of idiopathic inflammatory demyelinating disease (IIDDs) of the central nervous system in children, involving the brain, optic nerve and spinal cord. MOGAD requires individualized clinical management and specific treatment regimens, but its clinical manifestations overlap with other subtypes of IIDDs, making clinical identification difficult. MRI has the advantages of high soft tissue resolution and multi-parameter and multi-sequence imaging, which can better display the differences of neuroimaging characteristics between MOGAD and other subtypes of IIDDs, and plays an important role in the diagnosis and differential diagnosis of MOGAD. In recent years, studies on MOGAD have mainly focused on the summary and induction of imaging features of brain, optic nerve and spinal cord lesions based on MRI conventional sequences, while few studies on new sequences and new technologies have been performed on MOGAD in children. Therefore, this paper reviews the clinical and MRI research progress of MOGAD in children, in order to improve the level of understanding of the disease.
[Keywords] children；demyelinating diseases；myelin oligodendrocyte glycoprotein antibody disease；magnetic resonance imaging

LI Ting   CHEN Xin   WANG Haoru   HE Ling*  

Department of Radiology, Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Pediatrics, Chongqing 400014, China

*He L, E-mail: heling508@sina.com

Conflicts of interest   None.

ACKNOWLEDGMENTS Chongqing Municipal Education Commission Science and Technology Research Project (No. KJQN202000440); Chongqing Yuzhong District Basic Research and Frontier Exploration Project (No. 20200155).
Received  2022-05-16
Accepted  2022-07-26
DOI: 10.12015/issn.1674-8034.2022.09.029
Cite this article as: Li T, Chen X, Wang HR, et al. Research progress of MRI on myelin oligodendrocyte glycoprotein antibody disease in children[J]. Chin J Magn Reson Imaging, 2022, 13(9): 123-126. DOI:10.12015/issn.1674-8034.2022.09.029.

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