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Research progress of MRI in major depressive disorder with insomnia
FENG Jiejie  MA Laiyang  XU Lili  ZHANG Jing 

Cite this article as: Feng JJ, Ma LY, Xu LL, et al. Research progress of MRI in major depressive disorder with insomnia[J]. Chin J Magn Reson Imaging, 2022, 13(12): 141-145. DOI:10.12015/issn.1674-8034.2022.12.026.


[Abstract] Major depressive disorder (MDD) is one of the most common severe psychiatric disorders and is also an important cause of disability. Insomnia is not only a common symptom of MDD, but also the key factor in its recurrence, disability and suicide. With the development of neuroimaging and MRI technology, it is possible to elucidate the neuropathological mechanisms and associations of MDD with insomnia. In this paper, several advanced MRI techniques are used to review the current research progress of MDD with insomnia from the aspects of structure, function, metabolism and brain functional network, in order to provide imaging evidence for the interpretation of the pathological mechanism and optimize clinical decision making, and provide some new ideas for future researches.
[Keywords] major depressive disorder；insomnia；brain function；functional magnetic resonance imaging；resting-state functional magnetic resonance imaging；diffusion tensor imaging；magnetic resonance spectrum；magnetic resonance imaging

FENG Jiejie1, 2   MA Laiyang1, 2   XU Lili1, 2   ZHANG Jing1*  

1 Department of Magnetic Resonance, Lanzhou University Second Hospital, Lanzhou 730030, China

2 The Second Clinical Medicine College of Lanzhou University, Lanzhou 730000, China

Zhang J, E-mail: lztong2001@163.com

Conflicts of interest   None.

Received  2022-05-31
Accepted  2022-10-09
DOI: 10.12015/issn.1674-8034.2022.12.026
Cite this article as: Feng JJ, Ma LY, Xu LL, et al. Research progress of MRI in major depressive disorder with insomnia[J]. Chin J Magn Reson Imaging, 2022, 13(12): 141-145. DOI:10.12015/issn.1674-8034.2022.12.026.

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