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From research to clinic: The huge potential about application of magnetic resonance imaging in neurodegenerative disease
TIAN Yaotian  LI Chunmei  CHEN Min 

Cite this article as: TIAN Y T, LI C M, CHEN M. From research to clinic: The huge potential about application of magnetic resonance imaging in neurodegenerative disease[J]. Chin J Magn Reson Imaging, 2023, 14(1): 1-5, 19. DOI:10.12015/issn.1674-8034.2023.01.001.


[Abstract] The continuous advances in MRI technology can provide new insights into brain about morphological structure, perfusion, white matter and axonal microstructure, neuronal activity and multiple metabolite loads, which has led to its widely implementation in neurodegenerative diseases. This paper reviewed the application and research status of MRI technology in neurodegenerative diseases, delineated its potential pathophysiological mechanisms, emphasized its role in the diagnosis, differentiation and progress prediction of neurodegenerative diseases. Meanwhile, it pointed out the challenges these technologies faced in transforming from scientific research to clinical application, and given the prospect of future development of MRI technology in neurodegenerative diseases.
[Keywords] neurodegenerative diseases；Alzheimer's disease；Parkinson's disease；multisystem atrophy；amyotrophic lateral sclerosis；magnetic resonance imaging；structural magnetic resonance imaging；arterial spin labeling；diffusion tensor imaging；quantitative susceptibility mapping；blood oxygen level dependent；chemical exchange saturation transfer；magnetic resonance spectroscopy；research progress

TIAN Yaotian1, 2   LI Chunmei1, 2   CHEN Min1, 2*  

1 Department of Radiology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing 100730, China

2 Graduate School of Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China

Corresponding author: Chen M, E-mail: cjr.chenmin@vip.163.com

Conflicts of interest   None.

ACKNOWLEDGMENTS National Natural Science Foundation of China (No. 82071891, 81771826).
Received  2022-09-20
Accepted  2022-12-30
DOI: 10.12015/issn.1674-8034.2023.01.001
Cite this article as: TIAN Y T, LI C M, CHEN M. From research to clinic: The huge potential about application of magnetic resonance imaging in neurodegenerative disease[J]. Chin J Magn Reson Imaging, 2023, 14(1): 1-5, 19. DOI:10.12015/issn.1674-8034.2023.01.001.

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