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• Clinical Article •
Quantitative evaluation of abdominal fat distribution and visceral fat in young people based on mLIVE sequence
WU Hang  ZHOU Taohu  LI Yubiao  GAO Jun  HUANG Wenjun  WANG Yun  DONG Peng  SONG Limei 

Cite this article as: WU H, ZHOU T H, LI Y B, et al. Quantitative evaluation of abdominal fat distribution and visceral fat in young people based on mLIVE sequence[J]. Chin J Magn Reson Imaging, 2023, 14(1): 77-81. DOI:10.12015/issn.1674-8034.2023.01.014.


[Abstract] Objective To quantitatively investigate the visceral fat area (VFA), subcutaneous fat area (SFA), the fat deposition of liver, pancreas, kidney and vertebral body in healthy adults by using multi echo liver interpolated volume excitation (mLIVE), and explore the relationship between them.Materials and Methods Forty-five volunteers (26 females and 19 males) were recruited and scanned using mLIVE sequence. The height and the body weight of the volunteers were measured. The body mass index (BMI) and the fat fraction (FF) of liver, pancreas, kidney and vertebral body were calculated by two observers. VFA and SFA at the L2 vertebral body plane of each subject were measured using ImageJ software (U.S. Institute of Health) by two observers. Pearson correlation analyses were used to explore the relationship between BMI and MRI-derived fat measurements, and the relationship between MRI-derived fat measurements.Results The data measured by the two observers were consistently good (intra-class correlation coefficients＞0.75). Correlation analysis revealed that BMI were correlated significantly with VFA (r=0.677, P＜0.05) and SFA (r=0.781, P＜0.05). No correlations were found between BMI and the FF values of liver and pancreas (P＞0.05). VFA, SFA and pancreas FF were correlated with the FF values of liver (P＜0.05) respectively, and the pancreas FF had best correlation with the liver FF (r=0.449, P＜0.05). VFA was correlated significantly with SFA (r=0.575, P＜0.05) and vertebral FF (r=0.349, P＜0.05), respectively.Conclusions Although BMI can roughly evaluate the adipose tissue distribution in healthy adults, it is not accurate in estimating the fat content of internal organs. A positive correlation between VFA and the FF values of liver illustrating that the increased abdominal visceral fat play an important role in the occurrence of liver fat deposition. The FF of liver and pancreas was positively correlated in healthy adults demonstrating that liver fat deposition is of great significance on the pancreas fat deposition. The relationship between VFA and the FF values of lumbar vertebral indicating that abdominal obesity may easily affect the fat content of lumbar bone marrow. This study shed new light on the relationship between fat content in different organs and tissues of healthy adults, help further understand fat metabolism in healthy adults, and provide more information and evidence for clinical risk prediction and early prevention of metabolic syndrome.
[Keywords] liver；pancreas；lumbar vertebrae；fat quantification；visceral fat；fat fraction；metabolic syndrome；magnetic resonance imaging

WU Hang1   ZHOU Taohu1   LI Yubiao1   GAO Jun1   HUANG Wenjun1   WANG Yun1, 2   DONG Peng1   SONG Limei1*  

1 College of Medical Imaging, Weifang Medical University, Weifang 261053,China

2 Imaging Center, Affiliated Hospital of Weifang Medical University, Weifang 261031, China

Corresponding author: Song LM, E-mail: Songlm@wfmu.edu.cn

Conflicts of interest   None.

ACKNOWLEDGMENTS Natural Science Foundation youth Fund of Shandong Provincial (No. ZR2020QH048); Weifang Science and Technology Development Plan Project (No. 2020YX036).
Received  2022-09-02
Accepted  2022-12-09
DOI: 10.12015/issn.1674-8034.2023.01.014
Cite this article as: WU H, ZHOU T H, LI Y B, et al. Quantitative evaluation of abdominal fat distribution and visceral fat in young people based on mLIVE sequence[J]. Chin J Magn Reson Imaging, 2023, 14(1): 77-81. DOI:10.12015/issn.1674-8034.2023.01.014.

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