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Research progress of magnetic resonance imaging in the identification and evaluation of ischemic penumbra in acute cerebral infarction
WANG Yanting  YU Hao 

Cite this article as: WANG Y T, YU H. Research progress of magnetic resonance imaging in the identification and evaluation of ischemic penumbra in acute cerebral infarction[J]. Chin J Magn Reson Imaging, 2023, 14(1): 161-165. DOI:10.12015/issn.1674-8034.2023.01.030.


[Abstract] Acute ischemic stroke (AIS), also known as acute cerebral infarction, is one of the most common type of stroke in China, with high mortality and disability rate. As the target of reperfusion therapy for acute cerebral infarction, the early and accurate identification of ischemic penumbra is of great significance for clinicians to make reasonable treatment plan and prognosis evaluation. In recent years, a variety of mismatched models based on MRI sequences have studied how to identify the ischemic penumbra early and accurately from the perspectives of hemodynamics, collateral circulation and metabolism. This article reviews the research progress of these models in the evaluation of ischemic penumbra, aiming to provide directions for future research.
[Keywords] acute cerebral infarction；ischemic penumbra；magnetic resonance imaging；perfusion weighted imaging；susceptibility weighted imaging；amide proton transfer imaging

WANG Yanting1   YU Hao2*  

1 Clinical Medical College of Jining Medical University, Jining 272013, China

2 Department of Medical Imaging, Affiliated Hospital of Jining Medical University, Jining 272029, China

Corresponding author: Yu H, E-mail: ssyuhao@126.com

Conflicts of interest   None.

ACKNOWLEDGMENTS National Natural Science Foundation of China (No. 82001805); Doctoral Research Foundation of Affiliated Hospital of Jining Medical Universitiy (No. 2018-BS-010).
Received  2022-05-10
Accepted  2022-12-12
DOI: 10.12015/issn.1674-8034.2023.01.030
Cite this article as: WANG Y T, YU H. Research progress of magnetic resonance imaging in the identification and evaluation of ischemic penumbra in acute cerebral infarction[J]. Chin J Magn Reson Imaging, 2023, 14(1): 161-165. DOI:10.12015/issn.1674-8034.2023.01.030.

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