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Research advances in MRI for cognitive impairment in children with self-limited epilepsy with centrotemporal spikes
YIN Yu  LIU Heng 

Cite this article as: YIN Y, LIU H. Research advances in MRI for cognitive impairment in children with self-limited epilepsy with centrotemporal spikes[J]. Chin J Magn Reson Imaging, 2023, 14(2): 153-157. DOI:10.12015/issn.1674-8034.2023.02.027.


[Abstract] Self-limited epilepsy with centrotemporal spikes (SLECTS) is the most common childhood focal epilepsy syndrome associated with a series of cognitive and behavioral deficits. Its pathogenesis is still unclear and clinical interventions are controversial. With advances in neuroimaging technology and the widespread use of novel MRI techniques, structural and functional brain alterations in SLECTS and their correlation with cognitive impairment have become a hot research topic today. The transdisciplinary model of electroencephalogram-functional MRI (EEG-fMRI) technology combined with genomics and artificial intelligence will be a major direction for future SLECTS research, which is expected to further elucidate the neuropathological mechanisms underlying the occurrence of cognitive dysfunction in SLECTS and provide a more definitive clinical basis for early diagnosis and individualized treatment. Therefore, this article reviews the current status and potential weaknesses of MRI research in SLECTS to provide a reference for future research.
[Keywords] self-limited epilepsy with centrotemporal spikes；magnetic resonance imaging；structural magnetic resonance imaging；functional magnetic resonance imaging；diffusion tensor imaging

YIN Yu   LIU Heng*  

Department of Radiology, the Affiliated Hospital of Zunyi Medical University, Medical Imaging Center of Guizhou Province, Zunyi 563003, China

*Correspondence to: Liu H, E-mail: zmcliuh@163.com

Conflicts of interest   None.

ACKNOWLEDGMENTS Young Outstanding Scientific and Technological Talent Training Program of Guizhou Province (No. Qian Ke He Pingtai Rencai〔2021〕5620); Graduate Student Scientific Research Innovation Projects in Guizhou Province (No. Qian Jiao He YJSKYJJ〔2021〕184).
Received  2022-09-15
Accepted  2023-02-01
DOI: 10.12015/issn.1674-8034.2023.02.027
Cite this article as: YIN Y, LIU H. Research advances in MRI for cognitive impairment in children with self-limited epilepsy with centrotemporal spikes[J]. Chin J Magn Reson Imaging, 2023, 14(2): 153-157. DOI:10.12015/issn.1674-8034.2023.02.027.

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