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Research progress in MRI of microbiota‐gut‐brain axis dysbiosis
LIU Wanting  ZHANG Xiaoling 

Cite this article as: LIU W T, ZHANG X L. Research progress in MRI of microbiota‐gut‐brain axis dysbiosis[J]. Chin J Magn Reson Imaging, 2023, 14(2): 158-162. DOI:10.12015/issn.1674-8034.2023.02.028.


[Abstract] The gut‐brain axis is a bidirectional information communication pathway. As one of the key regulators of the gut‐brain axis, the gut microbiota is not only involved in maintaining intestinal homeostasis and regulating intestinal function, but also can directly communicate and transmit information with the brain through the complex enteric nervous system. At present, studies have confirmed that the dysbiosis of intestinal microbiota may be related to neurodegenerative diseases, mental and metabolic diseases, but the mechanism behind it has not been clearly elucidated. Focusing on the role and research progress of magnetic resonance imaging technology in dysbiosis of intestinal microbiota and neurodegenerative disorders, psychosocial and metabolic diseases, this paper summarizes the correlation between intestinal microflora and brain structure and function, aiming to explore the action mechanism of intestinal microbes in diseases and provide theoretical support in clinical treatment.
[Keywords] gut microbial communities；gut-brain axis；magnetic resonance imaging；functional magnetic resonance imaging；multimodal magnetic resonance imaging

LIU Wanting1   ZHANG Xiaoling2*  

1 Graduate School of Xi'an Medical University, Xi'an 710068, China

2 MRI Room of Shaanxi Provincial People's Hospital, Xi'an 710068, China

*Correspondence to: Zhang XL, E-mail: zxl.822@163.com

Conflicts of interest   None.

ACKNOWLEDGMENTS National Natural Science Foundation of China (No. 82170820); Key Research and Development Plan of Shaanxi (No. 2018ZDXM-SF-038).
Received  2022-09-15
Accepted  2023-02-08
DOI: 10.12015/issn.1674-8034.2023.02.028
Cite this article as: LIU W T, ZHANG X L. Research progress in MRI of microbiota‐gut‐brain axis dysbiosis[J]. Chin J Magn Reson Imaging, 2023, 14(2): 158-162. DOI:10.12015/issn.1674-8034.2023.02.028.

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