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• Clinical Article •
Value of cardiac magnetic resonance feature tracking in the evaluation of ventricular function in uncomplicated obesity subjects
TANG Lu  WU Xi  PENG Pengfei  YUE Xun  PU Qian  YANG Huiyi  CHENG Zhong  CHEN Yi  SUN Jiayu 

Cite this article as: TANG L, WU X, PENG P F, et al. Value of cardiac magnetic resonance feature tracking in the evaluation of ventricular function in uncomplicated obesity subjects[J]. Chin J Magn Reson Imaging, 2023, 14(3): 88-94. DOI:10.12015/issn.1674-8034.2023.03.015.


[Abstract] Objective To explore the value of cardiac magnetic resonance feature tracking (CMR-FT) in the evaluation of left and right ventricular function in uncomplicated obesity subjects.Materials and Methods Cardiac magnetic resonance cine imaging was performed in 35 uncomplicated obesity subjects and 35 sex- and age-matched healthy volunteers. The CVI 42 software was used to measure left and ventricular routine cardiac function and myocardial strain parameters, as well as epicardial adipose tissue (EAT) area. The strain parameters, including circumferential, radial and longitudinal peak strain (PCS, PRS, PLS, respectively), peak diastolic strain rate (PCSR-D, PRSR-D, PLSR-D, respectively), peak systolic strain rate (PCSR-S, PRSR-S, PLSR-S, respectively), were measured. Student's t test or Mann-Whitney U test was applied for comparison between the two groups, and Spearman rank correlation analysis was used for correlation analysis. P＜0.05 were considered statistically significant.Results Compared with the control group, the uncomplicated obesity subjects had higher left and right ventricular EDV, ESV, LVmass, LVmassi and EAT area (all P＜0.05), but there was no significant difference in EDVi, ESVi and EF between the two groups. Meanwhile, the left and right ventricular global PRS, PCS, PRSR-S, PRSR-D, PCSR-D, PLSR-D and the left ventricular global PLS and PLSR-S were significantly decreased in obese group (all P＜0.05). The left and right ventricular EDV, ESV and LVmass were positively correlated with BMI and EAT area (all P＜0.001). The left and right ventricular global PRS, PCS, PRSR-S, PRSR-D, PCSR-D, PLSR-D and the left ventricular global PLS, PLSR-S were negatively correlated with BMI (all P＜0.05). The left and right ventricular global PCS, PLSR-S, PRSR-D, PCSR-D and the left ventricular PRS, PLS, PRSR-S, PLSR-D and were negatively correlated with EAT area (all P＜0.05).Conclusions The changes of left and right ventricular structure and subclinical function in uncomplicated obesity subjects were associated with BMI and EAT area. CMR-FT can evaluate the early changes of ventricular myocardial function in uncomplicated obesity subjects.
[Keywords] obesity；ventricular function；magnetic resonance imaging；cardiac magnetic resonance；feature tracking；myocardial strain

TANG Lu1   WU Xi1, 2   PENG Pengfei1   YUE Xun1, 2   PU Qian1   YANG Huiyi1, 2   CHENG Zhong3   CHEN Yi3   SUN Jiayu1*  

1 Department of Radiology, West China Hospital, Sichuan University, Chengdu 610041, China

2 Department of Radiology, Affiliated Hospital of North Sichuan Medical College, Nanchong 637000, China

3 Department of Gastrointestinal Surgery, West China Hospital, Sichuan University, Chengdu 610041, China

Corresponding author: Sun JY, E-mail: cardiac_wchscu@163.com

Conflicts of interest   None.

ACKNOWLEDGMENTS Science and Technology Plan Project of Sichuan Province (No. 2020YFS0123).
Received  2022-10-25
Accepted  2023-03-03
DOI: 10.12015/issn.1674-8034.2023.03.015
Cite this article as: TANG L, WU X, PENG P F, et al. Value of cardiac magnetic resonance feature tracking in the evaluation of ventricular function in uncomplicated obesity subjects[J]. Chin J Magn Reson Imaging, 2023, 14(3): 88-94. DOI:10.12015/issn.1674-8034.2023.03.015.

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