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• Clinical Article •
Evaluation of fetal spinal anatomy and vertebral deformity with 3 T magnetic resonance three-dimensional T2-weighted fast field echo sequence
HE Shuang  LEI Qiang  WANG Fang  ZHAO Xiaoli  WANG Zhigang  LAI Hua  WEN Xilin 

Cite this article as: HE S, LEI Q, WANG F, et al. Evaluation of fetal spinal anatomy and vertebral deformity with 3 T magnetic resonance three-dimensional T2-weighted fast field echo sequence[J]. Chin J Magn Reson Imaging, 2023, 14(3): 111-116. DOI:10.12015/issn.1674-8034.2023.03.019.


[Abstract] Objective To analyze the value of three-dimensional T2-weighted fast field echo (3D-T2*-FFE) in fetal spinal anatomy and vertebral deformity.Materials and Methods Fourty-six middle and late pregnant women, whose prenatal ultrasound showed abnormal fetal vertebral bodies or unclear spine parts, were consecutively enrolled. All fetuses underwent corresponding spinal MRI examination on a 3 T MR with a 16-channel body matrix coil. The scanning MR sequences included 3D-T2*-FFE, two-dimensional single shot fast spin echo (2D SSH TSE) and two-dimensional balance turbo fast field echo (2D BTFE), region of interest (ROI) was carefully delineated for all cases to calculate the signal difference ratio of the corresponding vertebral bodies and intervertebral discs in the cervical, thoracic and lumbar segments with the three sequences respectively to evaluate image contrast.Results Compared with 2D SSH TSE sequence and 2D BTFE sequence, 3D-T2*-FFE sequence could obtain better image quality of fetal cervical vertebra. The image quality of 2D BTFE and 3D-T2*-FFE sequence was superior to that of 2D SSH TSE sequence in fetal thoracic vertebra and lumbosacral vertebra. The signal difference ratio values of 3D-T2*-FFE and 2D BTFE sequences were higher than those of 2D SSH TSE sequences, and the difference was statistically significant (P＜0.05); The signal difference ratio values of thoracic vertebra and lumbar vertebra showed no significant difference in each sequence (P＞0.05).Conclusions 3D-T2*-FFE sequences have better imaging effects on fetal vertebra under 3 T MRI, but 3D-T2*-FFE sequences can display more anatomical details of the spine. It is not affected by fetal position, and the scanning time is short, so it can be used as an important complementary sequence in clinical MRI of fetal spine.
[Keywords] prenatal diagnosis；fetal vertebra；vertebral deformity；magnetic resonance imaging；three-dimensional imaging；T2-weighted fast field echo

HE Shuang   LEI Qiang   WANG Fang   ZHAO Xiaoli   WANG Zhigang   LAI Hua   WEN Xilin*  

Department of Radiology, Chengdu Women's and Children's Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu 611731, China

Corresponding author: Wen XL, E-mail: xilin.wen@163.com

Conflicts of interest   None.

Received  2022-07-28
Accepted  2023-02-23
DOI: 10.12015/issn.1674-8034.2023.03.019
Cite this article as: HE S, LEI Q, WANG F, et al. Evaluation of fetal spinal anatomy and vertebral deformity with 3 T magnetic resonance three-dimensional T2-weighted fast field echo sequence[J]. Chin J Magn Reson Imaging, 2023, 14(3): 111-116. DOI:10.12015/issn.1674-8034.2023.03.019.

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