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• Clinical Article •
Study of the value of MR T2 mapping in the evaluation of peripheral muscle changes in knee osteoarthritis
LI Junfei  WANG Yijing  ZHANG Xuesong  REN Congcong  HOU Zishuo  ZHAO Jian  CUI Jianling  YU Hong 

Cite this article as: LI J F, WANG Y J, ZHANG X S, et al. Study of the value of MR T2 mapping in the evaluation of peripheral muscle changes in knee osteoarthritis[J]. Chin J Magn Reson Imaging, 2023, 14(3): 117-121, 133. DOI:10.12015/issn.1674-8034.2023.03.020.


[Abstract] Objective To analyze the change of T2 value of periknee muscle in patients with knee osteoarthritis (KOA) and its relationship with the severity of KOA based on T2 mapping.Materials and Methods In this study, 38 patients with KOA and 16 healthy volunteers were prospectively recruited for knee MR examination and peripheral muscle T2 mapping sequence scanning, to compare the differences in muscle T2 between the two groups, and to analyze the correlation between each muscle T2 values and the severity of KOA. Whole-Organ Magnetic Resonance Imaging Score (WORMS) was used to evaluate the severity of KOA. The higher the WORMS, the higher the severity of structural damage. The relationship between T2 values of each muscle and WORMS of knee joint was analyzed. At the same time, the correlation between the articular cartilage and submarrow edema scores and T2 values of each muscle was analyzed.Results The T2 values of the muscles around the knee joint in KOA patients were higher than those in healthy volunteers. The correlation analysis between muscle T2 value and WORMS showed that the T2 values of sartorius muscle, vastus medialis, muscle, and gastrocnemius medial head were positively correlated with WORMS (r=0.678, 0.674, 0.466, P＜0.05) and articular cartilage score (r=0.590, 0.672, 0.424, P＜0.05); T2 values of sartorius and vastus medialis were positively correlated with subarticular bone marrow edema (r=0.527, 0.538, P＜0.05). Hemiembranial muscle T2 value was positively correlated with articular cartilage score (r=0.347, P＜0.05).Conclusions MR T2 mapping can sensitively and quantitatively assess the muscle changes around the knee in patients with KOA. As the severity of KOA increases, T2 values in some muscles increase. T2 value of skeletal muscle can be used as a sensitive index to reflect the changes of internal structure and composition of skeletal muscle in KOA patients.
[Keywords] knee joint；osteoarthritis；T2 mapping；muscle；magnetic resonance imaging

LI Junfei1   WANG Yijing2   ZHANG Xuesong1   REN Congcong1   HOU Zishuo1   ZHAO Jian1   CUI Jianling1   YU Hong1*  

1 Department of CT/MR, the Third Hospital of Hebei Medical University, Shijiazhuang 050051, China

2 Department of Radiology, Hebei General Hospital, Shijiazhuang 050051, China

Corresponding author: Yu H, E-mail: yhdoctor82@163.com

Conflicts of interest   None.

ACKNOWLEDGMENTS 2023 Hebei Provincial Medical Science Research Project (No. 20230088).
Received  2022-10-17
Accepted  2023-02-23
DOI: 10.12015/issn.1674-8034.2023.03.020
Cite this article as: LI J F, WANG Y J, ZHANG X S, et al. Study of the value of MR T2 mapping in the evaluation of peripheral muscle changes in knee osteoarthritis[J]. Chin J Magn Reson Imaging, 2023, 14(3): 117-121, 133. DOI:10.12015/issn.1674-8034.2023.03.020.

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