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• Clinical Article •
The diagnostic value of 3.0 T DCE-MRI combined with DWI in differentiating pleomorphic adenoma and basal cell adenoma of salivary gland
LI Sen  SHAO Shuo  YAN Xiaofan  WU Jianwei  ZHAO Xiaomeng  ZHENG Ning 

Cite this article as: LI S, SHAO S, YAN X F, et al. The diagnostic value of 3.0 T DCE-MRI combined with DWI in differentiating pleomorphic adenoma and basal cell adenoma of salivary gland[J]. Chin J Magn Reson Imaging, 2023, 14(4): 34-40. DOI:10.12015/issn.1674-8034.2023.04.007.


[Abstract] Objective To investigate the value of dynamic contrast-enhanced MRI (DCE-MRI) combined with diffusion-weighted imaging (DWI) in the differential diagnosis of salivary gland pleomorphic adenoma (PA) and basal cell adenoma (BCA).Materials and Methods Retrospective analysis of 55 cases with salivary gland tumors confirmed by pathology in Jining First People 's Hospital from December 2018 to August 2022, including 38 cases of PA and 17 cases of BCA. MRI data of all patients were collected and analyzed from picture archiving and communication system. The PA and BCA were compared and analyzed in time intensity curve (TIC) types, quantitative parameters [volume transfer constant (Ktrans), the rate constant (Kep), fractional volume of the extravascular-extracellular space (Ve), plasma fraction (Vp)] and apparent diffusion coefficient (ADC) value. Rreceiver operating characteristic (ROC) curve was used to evaluate the efficiency of DCE-MRI combined with DWI in distinguishing PA and BCA.Results The mean ADC value of PA [(1.74±0.36)×10-3 mm2/s] was higher than that of BCA [(1.32±0.13)×10-3 mm2/s], and the difference was statistically significant (P＜0.05). There were 5 cases of type B and 11 cases of type C in TIC of 17 cases of BCA, and 27 cases of type A, 10 cases of type C in 38 cases of PA. The Kep value of PA was lower than that of BCA and the Ve value of PA was higher than that of BCA (P＜0.05 ) in the quantitative parameters of DCE-MRI. There was no significant difference in Ktrans and Vp values between PA and BCA groups. The area under the curve (AUC) of ADC, TIC, Kep and Ve were 0.875, 0.808, 0.822 and 0.747, respectively. And the AUC of multi-parameter combination was 0.895-0.952.Conclusions TIC, Kep, Ve and ADC are all helpful to differentiate BCA and PA in salivary gland, and the combination of multiple parameters further improves its diagnostic efficiency.
[Keywords] salivary gland tumors；pleomorphic adenoma；basal cell adenoma；dynamic contrast-enhanced；magnetic resonance imagining；diffusion weighted imaging；quantitative parameter

LI Sen1   SHAO Shuo2   YAN Xiaofan1   WU Jianwei3   ZHAO Xiaomeng3   ZHENG Ning2*  

1 Shandong First Medical University (Shandong Academy of Medical Sciences), Jinan 250000, China

2 Department of Radiology, Jining First People's Hospital, Jining 272000, China

3 Clinical Medical College, Jining Medical College, Jining 272013, China

Corresponding author: Zheng N, E-mail: zhengning_369@163.com

Conflicts of interest   None.

ACKNOWLEDGMENTS Key Research and Development Program of Jining (No. 2021YXNS022).
Received  2022-11-25
Accepted  2023-04-11
DOI: 10.12015/issn.1674-8034.2023.04.007
Cite this article as: LI S, SHAO S, YAN X F, et al. The diagnostic value of 3.0 T DCE-MRI combined with DWI in differentiating pleomorphic adenoma and basal cell adenoma of salivary gland[J]. Chin J Magn Reson Imaging, 2023, 14(4): 34-40. DOI:10.12015/issn.1674-8034.2023.04.007.

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