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• Clinical Article •
Clinical application of DWI combined with DKI and SWI in the diagnosis of parotid tumors
YAN Xiaolan  YE Deqiu  CHEN Jieyun  LIU Jiyang  LIAN Tao 

Cite this article as: YAN X L, YE D Q, CHEN J Y, et al. Clinical application of DWI combined with DKI and SWI in the diagnosis of parotid tumors[J]. Chin J Magn Reson Imaging, 2023, 14(4): 41-45, 67. DOI:10.12015/issn.1674-8034.2023.04.008.


[Abstract] Objective To investigate the clinical application value of diffusion weighted imaging (DWI) combined with diffusion kurtosis imaging (DKI) and susceptibility weighted imaging (SWI) in the diagnosis and differential diagnosis of benign and malignant tumors of parotid gland.Materials and Methods A prospective study was conducted on 70 patients with parotid tumors confirmed by postoperative pathology in our hospital, including 48 benign tumors and 22 malignant tumors. All patients underwent conventional MRI examination, DWI, DKI, SWI sequence scan before surgery. Apparent diffusion coefficient (ADC) value, mean kurtosis (MK) value, radial kurtosis (Kr) value, axial kurtosis (Ka) value, venous distribution around tumor, susceptibility signal intensity (ITSS) grade, maximum venous diameter Dv-max and other technical indicators of functional imaging were analyzed by workstation. Receiver operating characteristic (ROC) curves were drawn for statistically significant results to analyze their diagnostic efficiency and obtain diagnostic thresholds.Results The ADC value of benign parotid tumor was higher than that of malignant tumor, and that of malignant tumor and Warthin tumor was lower than that of pleomorphic adenoma. The differences among all groups were statistically significant, with good diagnostic efficacy. The ADC value of Warthin tumor was close to that of malignant tumor, and there was no statistical significance between groups (P＜0.05). The mean values of MK, Kr and Ka in malignant parotid tumors were higher than those in benign tumors (P＜0.05), with statistical significance among all groups and good sensitivity and specificity. The venous distribution of benign parotid tumors was mainly peripheral, and that of malignant tumors was mainly central. The ITSS grade of benign tumors was mainly grade 1, and that of malignant tumors was mainly grade 2-3. The Dv-max of malignant tumors was higher than that of benign tumors, and the difference between each group was statistically significant (P＜0.05). In the joint diagnostic model of DKI, DWI and SWI, MK＞1.0400, Kr＞1.1500, Ka＞0.8670 and ADC＜1.140×10-3 mm2/s, the maximum vein diameter (Dv-max)＞1.500 mm, the area under the curve is 0.995, the sensitivity is 93.9%, and the specificity is 100.0%.Conclusions DWI, DKI, SWI combined diagnosis model can improve the differential diagnosis efficiency of benign and malignant parotid tumors.
[Keywords] parotid tumor；magnetic resonance imaging；diffusion weighted imaging；diffusion kurtosis imaging；susceptibility weighted imaging；diagnostic model；differential diagnosis

YAN Xiaolan   YE Deqiu   CHEN Jieyun*   LIU Jiyang   LIAN Tao  

Department of Radiology, Quanzhou First Hospital Affiliated to Fujian Medical University, Quanzhou 362000, China

Corresponding author: Chen JY, E-mail: 2207934327@qq.com

Conflicts of interest   None.

ACKNOWLEDGMENTS Science & Technology Program of Quanzhou City (No. 2019N029S).
Received  2022-11-02
Accepted  2023-04-12
DOI: 10.12015/issn.1674-8034.2023.04.008
Cite this article as: YAN X L, YE D Q, CHEN J Y, et al. Clinical application of DWI combined with DKI and SWI in the diagnosis of parotid tumors[J]. Chin J Magn Reson Imaging, 2023, 14(4): 41-45, 67. DOI:10.12015/issn.1674-8034.2023.04.008.

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