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Advances in the assessment of biological behaviors of endometrial carcinoma by IVIM-DWI and texture analysis
JIANG Xueyan  DONG Jiangning 

Cite this article as: JIANG X Y, DONG J N. Advances in the assessment of biological behaviors of endometrial carcinoma by IVIM-DWI and texture analysis[J]. Chin J Magn Reson Imaging, 2023, 14(5): 191-195. DOI:10.12015/issn.1674-8034.2023.05.034.


[Abstract] Recently, endometrial carcinoma, as the second malignant tumor of female reproductive system, its incidence and morbidity have been on the rise in our country, which seriously threatens the life and health of women. The biological behaviors of the endometrial carcinoma, such as pathological type, stage, grade and cell proliferation, are important factors affecting the diagnosis, treatment and prognosis of the patients. However, the evaluation of these biological behaviors often needs to be obtained by biopsy or post-operative pathology, which is not only invasive but also information-delayed. Therefore, it is manifested that an early non-invasive method to predict the biological behaviors of endometrial carcinoma is urgently necessary for clinical application, so as to guide the individualized treatment and prognostic evaluation of patients. Intravoxel incoherent motion diffusion weighted imaging (IVIM-DWI) can non-invasively evaluate the water molecule diffusion and microcirculation perfusion of tumor tissue at the molecular level. Texture analysis can objectively and quantitatively evaluate tumor heterogeneity from a microscopic perspective. IVIM-DWI and texture analysis provide pathophysiological information and microscopic level information for accurately predicting the biological behaviors of endometrial carcinoma, which makes up for the deficiency of biopsy and surgical pathology and is expected to provide new ideas for the diagnosis and treatment of endometrial carcinoma. This article reviews the latest research progress of IVIM-DWI and texture analysis techniques in predicting the biological behaviors of endometrial carcinoma in recent years. The application value of IVIM-DWI and texture analysis in evaluating the biological behaviors of endometrial carcinoma was analyzed from the histological typing, grading and Ki-67 expression of endometrial carcinoma, aiming to provide a basis for early non-invasive evaluation of patient prognosis and development of individualized treatment plans.
[Keywords] endometrial carcinoma；magnetic resonance imaging；intravoxel incoherent motion；diffusion weighted imaging；texture analysis；typing；grading；Ki-67

JIANG Xueyan1   DONG Jiangning1, 2*  

1 Bengbu Medical College Graduate School, Bengbu 233030, China

2 Department of Radiology, West Branch of the First Affiliated Hospital of University of Science and Technology of China (Anhui Provincial Cancer Hospital), Hefei 230031, China

Corresponding author: Dong JN, E-mail: dongjn@163.com

Conflicts of interest   None.

ACKNOWLEDGMENTS 2020 SKY Image Research Fund (No. Z-2014-07-2003-11); Key Research and Development Projects of Anhui Province (No. 2022e07020008); National Cancer Center Climbing Foundation for Clinical Research (No. NCC201912B03).
Received  2022-11-15
Accepted  2023-05-06
DOI: 10.12015/issn.1674-8034.2023.05.034
Cite this article as: JIANG X Y, DONG J N. Advances in the assessment of biological behaviors of endometrial carcinoma by IVIM-DWI and texture analysis[J]. Chin J Magn Reson Imaging, 2023, 14(5): 191-195. DOI:10.12015/issn.1674-8034.2023.05.034.

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