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Principle and application progress of magnetic resonance reporter gene imaging
SUN Jun  GUO Yi 

Cite this article as: SUN J, GUO Y. Principle and application progress of magnetic resonance reporter gene imaging[J]. Chin J Magn Reson Imaging, 2023, 14(6): 198-202. DOI:10.12015/issn.1674-8034.2023.06.036.


[Abstract] With the development of magnetic resonance imaging methods and the development of new sequences, magnetic resonance imaging has become increasingly widely used early diagnosis of diseases, cell tracing, and gene analysis. Magnetic resonance reporter gene imaging, as an important branch of magnetic resonance imaging, has also received great attention. There are various types of magnetic resonance imaging reporter genes, and their application fields vary due to their different imaging principles. Familiarity with the imaging principles and advantages and disadvantages of magnetic resonance imaging reporter genes is a prerequisite for their application. This article will introduce the application of reporter genes from the imaging principles, research frontiers, and future development of magnetic resonance reporter genes. We hope to improve the efficiency and safety of magnetic resonance molecular imaging and promote the development of magnetic resonance imaging technology.
[Keywords] magnetic resonance imaging；reporter gene；metal dependence；ferritin genes；chemical exchange saturation transfer

SUN Jun   GUO Yi*  

Department of Radiology, Chongqing University Central Hospital/Chongqing Emergency Medical Center, Chongqing 400014, China

Corresponding author: Guo Y, E-mail: YIGUO_0909@sina.com

Conflicts of interest   None.

ACKNOWLEDGMENTS Chongqing Natural Science Foundation (No. cstc2021jcyj-msxmX0841); Chongqing Science and Health Union (No. 2023MSXM016).
Received  2022-01-25
Accepted  2023-05-18
DOI: 10.12015/issn.1674-8034.2023.06.036
Cite this article as: SUN J, GUO Y. Principle and application progress of magnetic resonance reporter gene imaging[J]. Chin J Magn Reson Imaging, 2023, 14(6): 198-202. DOI:10.12015/issn.1674-8034.2023.06.036.

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