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• Clinical Articles •
Prediction of recurrence of craniopharyngioma within 5 years after operation based on preoperative MR radiomics model
ZHAN Dongwei  KONG Xin  LUO Yuqi  ZHANG Yu  MA Jun 

Cite this article as: ZHAN D W, KONG X, LUO Y Q, et al. Prediction of recurrence of craniopharyngioma within 5 years after operation based on preoperative MR radiomics model[J]. Chin J Magn Reson Imaging, 2023, 14(7): 37-41. DOI:10.12015/issn.1674-8034.2023.07.007.


[Abstract] Objective To investigate the MR radiomics models in predicting postoperative recurrence of craniopharyngioma within 5 years.Materials and Methods One hundred and sixty four patients who underwent surgical resection of craniopharyngioma were retrospective studied (87 cases with postoperative recurrence within five years, 77 cases without recurrence). The patients were divided into exercise group and test group as the proportion of 7∶3, Clinical characteristics of the patients were collected. 3D Slicer software was used to delineate region of interest (ROI) and extract radiomics features. Single factor analysis and least absolute shrinkage and selection operator (LASSO) were used for feature selection, and support vector machine (SVM) algorithm was used to establish the radiomics model and clinical model, the area under the curve (AUC) value was calculated and receiver operating characteristic (ROC) curve was drawn to evaluate the prediction efficacy of the model.Results In the training group, the AUC of radiomics model in predicting the recurrence of craniopharyngioma within 5 years after operation was 0.767 [95% confidence interva (CI): 0649-0.816], the sensitivity was 77%, and specificity was 71%. In the test group, the AUC of radiomics model in predicting the recurrence of craniopharyngioma within 5 years after operation was 0.770 (95% CI: 0.657-0.898), the sensitivity was 71%, and specificity was 86%.Conclusions The radiomics model based on contrast-enhanced T1-weighted imaging (CE-T1WI) is effective in predicting the recurrence of craniopharyngioma.
[Keywords] craniopharyngioma；magnetic resonance imaging；radiomics；recurrence；prediction

ZHAN Dongwei1, 2   KONG Xin2   LUO Yuqi2   ZHANG Yu2   MA Jun2*  

1 Department of Radiology, Beijing Pinggu District Hospital of Traditional Chinese Medicine, Beijing 101200, China

2 Department of Radiology, Beijing Tiantan Hospital, Capital Medical University, Beijing 100070, China

Corresponding author: Ma J, E-mail: dr.junma@foxmail.com

Conflicts of interest   None.

ACKNOWLEDGMENTS National Natural Science Foundation of China (No. 61771325).
Received  2022-12-27
Accepted  2023-06-28
DOI: 10.12015/issn.1674-8034.2023.07.007
Cite this article as: ZHAN D W, KONG X, LUO Y Q, et al. Prediction of recurrence of craniopharyngioma within 5 years after operation based on preoperative MR radiomics model[J]. Chin J Magn Reson Imaging, 2023, 14(7): 37-41. DOI:10.12015/issn.1674-8034.2023.07.007.

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