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Research progress and applications of fat quantification with magnetic resonance imaging
MA Mengyuan  WANG Jinyang  LI Xiaoben  FAN Zhuangzhuang  WANG Changqing 

Cite this article as: MA M Y, WANG J Y, LI X B, et al. Research progress and applications of fat quantification with magnetic resonance imaging[J]. Chin J Magn Reson Imaging, 2023, 14(7): 197-202. DOI:10.12015/issn.1674-8034.2023.07.036.


[Abstract] Due to unhealthy diet and lack of exercise, abnormal fat content in the human body has gradually become one of the important factors that endanger human health. Excessive fat accumulation around tissues and organs can destroy the information transmission system in the human body, and make tissues and organs transmit error signal to the body, leading to endocrine system function disturbances. Abnormal fat deposition is closely related to several chronic diseases, such as fatty liver, type 2 diabetes, hypertension and osteoporosis. Therefore, the accurate quantification of fat is of great clinical significance for the prevention, assessment, diagnosis and treatment of these diseases. The gold standard for accurate quantification of fat is biopsy, but it has certain invasive and sampling errors. In recent years, the research on fat quantification by magnetic resonance technology is deepening. We reviewed several magnetic resonance techniques, including magnetic resonance spectroscopy, adipose-inhibition imaging, water-fat separation techniques and proton density fat fraction, for fat quantification in different parts of human body (liver, pancreas, vertebral bone marrow and muscle) in this paper. This review aimed to provide an accurate biomarker for fat quantification, which would be helpful for accurate diagnosis and treatment in clinic.
[Keywords] magnetic resonance imaging；fat deposition；fat quantification；liver；pancreas；pyramidal bone marrow；muscle

MA Mengyuan   WANG Jinyang   LI Xiaoben   FAN Zhuangzhuang   WANG Changqing*  

School of Biomedical Engineering, Anhui Medical University, Hefei 230012, China

Corresponding author: Wang CQ, E-mail: wangchangqing@ahmu.edu.cn

Conflicts of interest   None.

ACKNOWLEDGMENTS National Natural Science Foundation of China (No. 62001005); Anhui Provincial Natural Science Foundation (No. 2008085QH425); Grants for Scientific Research of BSKY from Anhui Medical University (No. XJ201811).
Received  2022-08-25
Accepted  2023-05-30
DOI: 10.12015/issn.1674-8034.2023.07.036
Cite this article as: MA M Y, WANG J Y, LI X B, et al. Research progress and applications of fat quantification with magnetic resonance imaging[J]. Chin J Magn Reson Imaging, 2023, 14(7): 197-202. DOI:10.12015/issn.1674-8034.2023.07.036.

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