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• Clinical Article •
A preliminary study on diagnostic model of placenta implantation based on magnetic resonance image feature machine learning
WANG Yingchao  HUANG Gang  BA Zhixia  XUE Lian  HUANG Baosheng  XIA Dongzhou 

WANG Y C, HUANG G, BA Z X, et al. A preliminary study on diagnostic model of placenta implantation based on magnetic resonance image feature machine learning[J]. Chin J Magn Reson Imaging, 2023, 14(8): 94-99, 107. DOI:10.12015/issn.1674-8034.2023.08.015.


[Abstract] Objective To explore the diagnostic value of machine learning model based on MRI T2WI imaging features for placenta accrete spectrum disorders (PAS).Materials and Methods The imaging data of 130 patients who underwent MRI examination and later caesarean section due to suspected placenta accretion were retrospectively analyzed. According to the postoperative results of caesarean section, MRI T2WI images were used to extract the imaging features of the layers with and without placenta accretion. The data were divided into a training set (n=91) and a validation set (n=39) by stratified sampling in a ratio of 7∶3. Five machine learning methods were adopted: logistic regression (LR), support vector machine (SVM), random forest (RF), decision tree (DT) and K nearest neighbor (KNN) for modeling and classification diagnosis. The hyperparameters of the machine learning model were determined by five-fold cross-validation. Receiver operating characteristic (ROC) curve was adopted to evaluate the prediction efficiency of the model, calculated the area under the curve (AUC), accuracy, sensitivity and specificity, and verified each model in the verification set. In addition, in addition to comparing the diagnostic effectiveness of different machine learning models with that of imaging diagnostic doctors, calibration curves were used to analyze the model efficacy and decision curve analysis (DCA) was used to evaluate clinical practicability.Results Placenta accreta was confirmed in 56 patients after cesarean section, and in 74 patients without placenta accreta. Based on 1688 omics features included in the image preprocessing, 9 image omics features were selected for the construction of the model after least absolute shrinkage and selection operator (LASSO), Selectbest and REF processing. Five kinds of classifier models in the validation set (LR AUC=0.96, SVM AUC=0.97, RF AUC=0.99, DT AUC=0.87, KNN AUC=0.96) had higher diagnostic efficacy for placenta acta than that of imaging doctors (AUC=0.86). Calibration curves show that the calibration degree of RF models is best in the verification set. When the threshold value of validation set DCA is 0.0-0.6, the clinical net benefit of RF, SVM, KNN and LR models is greater than that of DT models.Conclusions The machine learning model based on MRI T2WI image features can accurately distinguish the presence or absence of placenta accretion, and its diagnostic efficacy is obviously better than that of physicians' visual analysis. In addition, compared with the five models, the RF machine learning model has better performance in the diagnosis of placenta accreta.
[Keywords] placenta accrete spectrum disorders；machine learning；diagnostic efficiency；magnetic resonance imaging

WANG Yingchao1   HUANG Gang2*   BA Zhixia1   XUE Lian3   HUANG Baosheng1   XIA Dongzhou1  

1 Department of Medical Imaging, Zhangye People's Hospital Affiliated to Hexi University, Zhangye 734000, China

2 Department of Radiology, Gansu Province Hospital, Lanzhou 730000, China

3 Department of Obstetrics, Zhangye People's Hospital Affiliated to Hexi University, Zhangye 734000, China

Corresponding author: Huang G, E-mail: keen0999@163.com

Conflicts of interest   None.

ACKNOWLEDGMENTS University Innovation Fund project of Education Department of Gansu Province (No. 2021B-232); Young Teachers Scientific Research Fund Project of Hexi University (No. QN2020005).
Received  2023-01-03
Accepted  2023-07-21
DOI: 10.12015/issn.1674-8034.2023.08.015
WANG Y C, HUANG G, BA Z X, et al. A preliminary study on diagnostic model of placenta implantation based on magnetic resonance image feature machine learning[J]. Chin J Magn Reson Imaging, 2023, 14(8): 94-99, 107. DOI:10.12015/issn.1674-8034.2023.08.015.

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