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Association and mechanism of asymptomatic carotid stenosis with cognitive impairment as suggested by multimodal MRI
ZHANG Chi  HE Chao  SUN Jingting  YANG Guan  CUI Guangbin  WANG Wen 

ZHANG C, HE C, SUN J T, et al. Association and mechanism of asymptomatic carotid stenosis with cognitive impairment as suggested by multimodal MRI[J]. Chin J Magn Reson Imaging, 2023, 14(8): 140-144, 170. DOI:10.12015/issn.1674-8034.2023.08.024.


[Abstract] Asymptomatic carotid stenosis (ACS) is not truly "asymptomatic", which is closely related to cognitive function and may even lead to cognitive impairment. To prevent the further development of dementia, it is urgent to investigate the relationship between ACS and cognition. Compared with traditional magnetic resonance imaging (MRI), multimodal MRI can prompt brain function changes earlier before brain structure changes, and is widely used in exploring cognitive function. In this paper, we summarized the relevant literature and found that the studies of ACS mainly focused on functional connectivity and brain volume changes, and most of them were static analyses. Future research should focus more on dynamic analysis and comprehensive analysis of the mechanisms of cognitive impairment due to ACS by combining function and structure. In this paper, we analyzed the relationship between ACS and cognitive impairment from the perspective of multimodal MRI to provide new ideas for the assessment and treatment of ACS.
[Keywords] asymptomatic carotid stenosis；cognitive impairment；multimodal magnetic resonance imaging；carotid endarterectomy；magnetic resonance imaging；brain function；brain structure

ZHANG Chi1, 2   HE Chao1   SUN Jingting1, 2   YANG Guan2   CUI Guangbin2*   WANG Wen1, 2*  

1 Faculty of Medical Technology, Shannxi University of Chinese Medicine, Xianyang 712046, China

2 Department of Radiology, Tangdu Hospital, Air Force Medical University, Xi'an 710038, Shaanxi, China

Corresponding author: Wang W, E-mail: wangwen@fmmu.edu.cn

Conflicts of interest   None.

ACKNOWLEDGMENTS Second Affiliated Hospital of Air Force Military Medical University Innovation Development Funding (No. 2018LCYJ005).
Received  2023-03-30
Accepted  2023-06-29
DOI: 10.12015/issn.1674-8034.2023.08.024
ZHANG C, HE C, SUN J T, et al. Association and mechanism of asymptomatic carotid stenosis with cognitive impairment as suggested by multimodal MRI[J]. Chin J Magn Reson Imaging, 2023, 14(8): 140-144, 170. DOI:10.12015/issn.1674-8034.2023.08.024.

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