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Application of superparamagnetic iron oxide nanoparticle in the diagnosis and treatment of tumor
ZUO Rourou  CHEN Baiqing  SUN Hongzan 

ZUO R R, CHEN B Q, SUN H Z. Application of superparamagnetic iron oxide nanoparticle in the diagnosis and treatment of tumor[J]. Chin J Magn Reson Imaging, 2023, 14(8): 197-202. DOI:10.12015/issn.1674-8034.2023.08.035.


[Abstract] Superparamagnetic iron oxide nanoparticle (SPION) show great potential in tumor diagnosis, construction of multimodal tumor molecular imaging probes and treatment because of their unique properties, such as low toxicity, biocompatibility, strong magnetism and superior role in multi-functional mode. In the future, it can improve the specificity and sensitivity of tumor diagnosis and realize the integration of diagnosis and treatment. Based on the imaging mechanism and synthesis methods of SPION, we described some research progress of SPION in various targeted imaging, multimodal imaging and treatment of tumors in recent years, and looked forward to the future development prospect of SPION in tumor diagnosis and treatment in this paper, in order to better construct a new type of integrated tumor probe based on SPION in the future.
[Keywords] tumor；superparamagnetic iron oxide nanoparticle；diagnosis；treatment；magnetic resonance imaging

ZUO Rourou1   CHEN Baiqing2   SUN Hongzan1*  

1 Department of Radiology, Shengjing Hospital of China Medical University, Shenyang 110004, China

2 Department of Nuclear Medicine, People's Hospital of Liaoning Provincial, Shenyang 110000, China

Corresponding author: Sun HZ, E-mail: sunhongzan@126.com

Conflicts of interest   None.

ACKNOWLEDGMENTS National Natural Science Foundation of China (No. 82171910).
Received  2022-10-23
Accepted  2023-06-19
DOI: 10.12015/issn.1674-8034.2023.08.035
ZUO R R, CHEN B Q, SUN H Z. Application of superparamagnetic iron oxide nanoparticle in the diagnosis and treatment of tumor[J]. Chin J Magn Reson Imaging, 2023, 14(8): 197-202. DOI:10.12015/issn.1674-8034.2023.08.035.

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