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• Clinical Article •
Correlation between radiomics features on T2WI sequences and clinical features of recurrent acute pancreatitis
HU Yuntao  LIU Nian  HUANG Xiaohua 

HU Y T, LIU N, HUANG X H. Correlation between radiomics features on T2WI sequences and clinical features of recurrent acute pancreatitis[J]. Chin J Magn Reson Imaging, 2023, 14(9): 76-80. DOI:10.12015/issn.1674-8034.2023.09.013.


[Abstract] Objective To explore the correlation between radiomics features on T2WI sequences and clinical features of recurrent acute pancreatitis (RAP).Materials and Methods This retrospective study collected T2WI images of 200 patients with acute pancreatitis (AP), including 127 cases of primary AP and 73 cases of RAP. The patients were randomly divided into a training group (n=139) and a validation group (n=61) in a 7∶3 ratio. Clinical characteristics of both groups were collected. Feature selection was performed using univariate analysis and the least absolute shrinkage and selection operator (LASSO) algorithm. Spearman correlation analysis was used to analyze the correlation between the optimal radiomics features and clinical characteristics, with P＜0.05 indicating statistical significance.Results Nine statistically significant features were retained, including cluster tendency, variance, two correlations, short run low gray-level emphasis, range, total mean, surface area density, and quartile. Complications were strong positively correlated with range (r=0.606, 95% CI: 0.508-0.690; P＜0.01), total mean (r=0.606, 95% CI: 0.508-0.690; P＜0.01), and quartile (r=0.606, 95% CI: 0.508-0.690; P＜0.01), while gallstone were strong positively correlated with short run low gray-level emphasis (r=0.575, 95% CI: 0.470-0.663; P＜0.01). Hyperlipidemia was strong positively correlated with total mean (r=0.501, 95% CI: 0.386-0.601; P＜0.01) and quartile (r=0.575, 95% CI: 0.470-0.663; P＜0.01), and alcoholism was strong positively correlated with range (r=0.699, 95% CI: 0.618-0.765; P＜0.01), total mean (r=0.822, 95% CI: 0.770-0.864; P＜0.01), and quartile (r=0.699, 95% CI: 0.618-0.765; P＜0.01).Conclusions Complications, stones, hyperlipidemia, and alcoholism are potential biological explanations for the radiomics features of RAP.
[Keywords] recurrent acute pancreatitis；magnetic resonance imaging；radiomics；biological significance

HU Yuntao1, 2   LIU Nian2   HUANG Xiaohua2*  

1 Department of Radiology, Affiliated Cancer Hospital of University of Electronic Science and Technology, Sichuan Cancer Hospital, Chengdu 610000, China

2 Department of Radiology, Affiliated Hospital of North Sichuan Medical College, Nanchong 637000, China

Corresponding author: Huang XH, E-mail: 15082797553@163.com

Conflicts of interest   None.

ACKNOWLEDGMENTS Sichuan Province Science and Technology Innovation Seedling Project (No. 2020088).
Received  2023-04-17
Accepted  2023-08-09
DOI: 10.12015/issn.1674-8034.2023.09.013
HU Y T, LIU N, HUANG X H. Correlation between radiomics features on T2WI sequences and clinical features of recurrent acute pancreatitis[J]. Chin J Magn Reson Imaging, 2023, 14(9): 76-80. DOI:10.12015/issn.1674-8034.2023.09.013.

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