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Research progress of magnetic resonance imaging in the assessment of TAO activity
ZHANG Yingcong  BI Qiu  GONG Xiarong  ZHANG Jie  LI Qingrui  WANG Qian  LI Chenrong  CHENG Changxin 

ZHANG Y C, BI Q, GONG X R, et al. Research progress of magnetic resonance imaging in the assessment of TAO activity[J]. Chin J Magn Reson Imaging, 2023, 14(9): 125-130. DOI:10.12015/issn.1674-8034.2023.09.023.


[Abstract] Thyroid-associated ophthalmopathy (TAO) is an autoimmune orbital disease. TAO affects the patient's appearance and even causes blindness, which reduces the patient's quality of life. The assessment of its disease activity and symptom severity is the basis for formulating treatment plans. Clinical activity score is mainly used to evaluate the stage of TAO. The imaging manifestations of TAO patients are mainly exophthalmos, extraocular myoedema thickening and orbital lipopedema, and other manifestations may be combined with enlarged tear gland volume, eyelid and optic nerve edema. Multi-modal MRI techniques such as T2WI fat suppression sequence, dynamic enhanced MRI, diffusion magnetic resonance imaging, mapping, magnetization transfer imaging and artificial intelligence analysis based on MRI images can provide more objective information for the activity staging of TAO from a variety of perspectives. In this paper, we summarized the application of these techniques in the extraocular muscle, orbital fat, lacrimal gland and optic nerve of TAO patients, and combined with the measured parameter values to determine the stage of TAO. It is of great significance to guide clinical decision-making, and is expected to provide reference direction for future research.
[Keywords] thyroid-associated ophthalmopathy；extraocular muscles；clinical activity score；magnetic resonance imaging；functional magnetic resonance imaging；diagnostic imaging；artificial intelligence

ZHANG Yingcong1   BI Qiu2   GONG Xiarong1, 2*   ZHANG Jie2   LI Qingrui1   WANG Qian1   LI Chenrong1   CHENG Changxin1  

1 College of Medicine, Kunming University of Science and Technology, Kunming 650000, China

2 Department of MRI, the First People's Hospital of Yunnan Province (the Affiliated Hospital of Kunming University of Science and Technology), Kunming 650032, China

Corresponding author: Gong XR, E-mail: 13888509243@163.com

Conflicts of interest   None.

ACKNOWLEDGMENTS Yunnan Health Training Project of High Level Talents (No. H-2019070).
Received  2023-04-18
Accepted  2023-09-06
DOI: 10.12015/issn.1674-8034.2023.09.023
ZHANG Y C, BI Q, GONG X R, et al. Research progress of magnetic resonance imaging in the assessment of TAO activity[J]. Chin J Magn Reson Imaging, 2023, 14(9): 125-130. DOI:10.12015/issn.1674-8034.2023.09.023.

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