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Application of resting-state functional MRI in the study of mild traumatic brain injury
ZENG Zhe  LUO Lin  CHEN Qiang 

Cite this article as: ZENG Z, LUO L, CHEN Q. Application of resting-state functional MRI in the study of mild traumatic brain injury[J]. Chin J Magn Reson Imaging, 2023, 14(10): 167-170. DOI:10.12015/issn.1674-8034.2023.10.030.


[Abstract] Mild traumatic brain injury (mTBI) is one of the most common traumatic diseases of the nervous system and can be defined as damage to the microstructure of brain tissue with dysfunction. Conventional imaging techniques are used to evaluate mTBI patients with a high false-negative rate, and advanced MRI techniques have great potential for mTBI injury detection and prognosis prediction. The advantage of resting-state functional MRI (rs-fMRI) is that it can detect abnormalities in brain function even when the structural imaging results are not significant. This paper focuses on the usefulness of voxel-based index analysis of rs-fMRI in mTBI patients. These indicators include amplitude of low-frequency fluctuations (ALFF), fractional ALFF (fALFF), regional homogeneity (ReHo) and functional connectivity (FC), and the advantages and disadvantages of each index are summarized in this paper to provide directions for future research.
[Keywords] mild traumatic brain injury；resting-state functional magnetic resonance imaging；magnetic resonance imaging；cognitive impairment；functional connection

ZENG Zhe   LUO Lin*   CHEN Qiang  

Department of Medical Imaging, the First Affiliated Hospital of Baotou Medical College, Inner Mongolia University of Science & Technology, Baotou 014010, China

Corresponding author: LUO L, E-mail: byll117@sina.com

Conflicts of interest   None.

ACKNOWLEDGMENTS Inner Mongolia Autonomous Region Education Department Fund (No. NJZY23021).
Received  2023-06-26
Accepted  2023-09-28
DOI: 10.12015/issn.1674-8034.2023.10.030
Cite this article as: ZENG Z, LUO L, CHEN Q. Application of resting-state functional MRI in the study of mild traumatic brain injury[J]. Chin J Magn Reson Imaging, 2023, 14(10): 167-170. DOI:10.12015/issn.1674-8034.2023.10.030.

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