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• Clinical Article •
Preliminary study on the diagnosis of 3D BH-GRASE sequence MRCP in extrahepatic cholelithiasis
XU Yichao  YIN Lijun  XU Zhengdao  HUANG Qiuya  ZHU Chenjie  CHEN Jianxin  HU Yijiang 

Cite this article as: XU Y C, YIN L J, XU Z D, et al. Preliminary study on the diagnosis of 3D BH-GRASE sequence MRCP in extrahepatic cholelithiasis[J]. Chin J Magn Reson Imaging, 2023, 14(11): 62-67, 83. DOI:10.12015/issn.1674-8034.2023.11.011.


[Abstract] Objective To compare clinical value of magnetic resonance cholangiopancreatography (MRCP) using three-dimensional respiratory-triggered turbo spin-echo (3D RT-TSE) sequence and three-dimensional breath-hold gradient and spin-echo (3D BH-GRASE) sequence in the diagnosis of extrahepatic cholelithiasis.Materials and Methods A retrospective analysis was made on 74 patients who underwent MRCP due to clinical suspicion of cholelithiasis at the Affiliated Zhangjiagang Hospital of Soochow University from November 2017 to November 2022. Both 3D RT-TSE and 3D BH-GRASE sequences were employed for MRCP. Images of the two sequences were evaluated by three radiologists with 3, 6 and 9 years of experience in abdominal MRI, respectively. Three radiologists independently evaluated the overall image quality of the acquired images and assessed the diagnostic quality of images suitable for diagnosis. The Wilcoxon signed-rank test was utilized to compare the overall image quality of the two sequences. The McNemar's test was employed to assess the differences in results obtained by the readers using the two imaging methods.Results The overall quality scores of 3D BH-GRASE MRCP images were superior to those of 3D RT-TSE MRCP images (Z=-7.286, P＜0.001). In the diagnosis of gallbladder stones, the sensitivity, specificity and accuracy of 3D BH-GRASE MRCP were 92.3%, 89.7% and 91.2%, respectively, while for 3D RT-TSE MRCP, these values were 66.7%, 86.2% and 75.0%, respectively. The difference of sensitivity, and accuracy between the two groups was statistically significant (P≤0.002), but the difference of specificity was statistically insignificant (P=0.317). In the diagnosis of extrahepatic bile duct stones, the sensitivity, specificity and accuracy of 3D BH-GRASE MRCP were 72.7%, 91.3% and 85.3% respectively, whereas for 3D RT-TSE MRCP, these values were 68.2%, 91.3% and 83.3%, respectively. There was no significant difference between them (P＞0.05).Conclusions 3D BH-GRASE MRCP is superior to 3D RT-TSE MRCP in the detection of extrahepatic cholelithiasis. Reasonable optimization of MRCP sequence could enhance the efficiency of examination and diagnostic efficacy.
[Keywords] cholelithiasis；magnetic resonance imaging；magnetic resonance cholangiopancreatography；diagnosis

XU Yichao   YIN Lijun   XU Zhengdao   HUANG Qiuya   ZHU Chenjie   CHEN Jianxin   HU Yijiang*  

Department of Radiology, the Affiliated Zhangjiagang Hospital of Soochow University, Suzhou 215600, China

Corresponding author: HU Y J, E-mail: yijiang_hu@aliyun.com

Conflicts of interest   None.

ACKNOWLEDGMENTS Social Development Technology Innovation Research Project of Zhangjiagang Science and Technology Bureau (No. ZKS2142).
Received  2023-04-14
Accepted  2023-10-27
DOI: 10.12015/issn.1674-8034.2023.11.011
Cite this article as: XU Y C, YIN L J, XU Z D, et al. Preliminary study on the diagnosis of 3D BH-GRASE sequence MRCP in extrahepatic cholelithiasis[J]. Chin J Magn Reson Imaging, 2023, 14(11): 62-67, 83. DOI:10.12015/issn.1674-8034.2023.11.011.

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