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Advancements in the multi-modal MRI study of probiotic formulations for ameliorating cognitive impairment in type 2 diabetes mellitus patients
WANG Xuyang  XU Shan  YANG Dong  LIN Lin  SHEN Jing  WU Jianlin 

Cite this article as: WANG X Y, XU S, YANG D, et al. Advancements in the multi-modal MRI study of probiotic formulations for ameliorating cognitive impairment in type 2 diabetes mellitus patients[J]. Chin J Magn Reson Imaging, 2023, 14(11): 159-163. DOI:10.12015/issn.1674-8034.2023.11.027.


[Abstract] Type 2 diabetes mellitus (T2DM) is the most common type of diabetes and is often accompanied by varying degrees of cognitive dysfunction. Research has shown a close relationship between the gut microbiota and the complications associated with T2DM. There is hope that cognitive dysfunction and other complications can be improved through the intervention of probiotics, and their assessment and evaluation can be achieved using multimodal MRI techniques. This article provides a comprehensive review of the current state of research and advancements in this field, aiming to offer new directions for personalized clinical diagnosis and treatment of cognitive impairments in T2DM and to provide new insights for research in the T2DM gut-brain-axis field.
[Keywords] type 2 diabetes mellitus；cognitive impairment；probiotics；mutimodal magnetic resonance imaging；magnetic resonance imaging；gut-brain-axis

WANG Xuyang   XU Shan   YANG Dong   LIN Lin   SHEN Jing   WU Jianlin*  

Department of Radiology, Affiliated Zhongshan Hospital of Dalian University, Dalian 116001, China

Corresponding author: WU J L, E-mail: cjr.wujianlin@vip.163.com

Conflicts of interest   None.

ACKNOWLEDGMENTS National Natural Science Foundation of China (No. 82071911); Dalian Municipal Science and Technology Innovation Fund (No. 2021JJ12SN38).
Received  2023-07-25
Accepted  2023-11-03
DOI: 10.12015/issn.1674-8034.2023.11.027
Cite this article as: WANG X Y, XU S, YANG D, et al. Advancements in the multi-modal MRI study of probiotic formulations for ameliorating cognitive impairment in type 2 diabetes mellitus patients[J]. Chin J Magn Reson Imaging, 2023, 14(11): 159-163. DOI:10.12015/issn.1674-8034.2023.11.027.

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