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Research progress of resting-state functional magnetic resonance imaging in the auxiliary diagnosis and early prognosis of bipolar disorder
GAO Yujun  SUN Jie  GUO Xin  LU Lin  WANG Gaohua 

Cite this article as: GAO Y J, SUN J, GUO X, et al. Research progress of resting-state functional magnetic resonance imaging in the auxiliary diagnosis and early prognosis of bipolar disorder[J]. Chin J Magn Reson Imaging, 2023, 14(12): 111-115. DOI:10.12015/issn.1674-8034.2023.12.019.


[Abstract] Bipolar disorder is a complex mental illness characterized by intricate clinical symptoms and treatment processes. With the rapid advancement of imaging techniques, bipolar disorder manifests distinct characteristics through various resting-state functional magnetic resonance imaging (rs-fMRI) analysis methods. Utilizing rs-fMRI research can offer deeper insights into the underlying pathogenesis of bipolar disorder and establish objective imaging biomarkers for clinical diagnosis, treatment response assessment, and prognosis prediction. This approach holds the potential to guide the development of novel mood stabilizing medications. This review article focused on recent rs-fMRI research in bipolar disorders, aiming to elucidate the current advancements in neural imaging related to bipolar disorder. Furthermore, it explored potential biomarkers and avenues for early treatment response prediction. The ultimate goal is to furnish clinicians with supplementary tools for diagnosing bipolar disorder and employing imaging indicators to forecast treatment efficacy.
[Keywords] bipolar disorder；magnetic resonance imaging；resting-state functional magnetic resonance imaging；pathogenesis；diagnosis；treatment efficacy

GAO Yujun1   SUN Jie2   GUO Xin1   LU Lin1, 3, 4   WANG Gaohua1*  

1 Department of Psychiatry, Renmin Hospital of Wuhan University, Wuhan 430060, China

2 Pain Medical Center, the Third Hospital of Peking University, Beijing 100191, China

3 Key Laboratory of Mental Health of the National Health Commission, National Clinical Medical Research Center for Mental Diseases, Mental Health Center of Peking University Sixth Hospital, Beijing 100191, China

4 Peking University Tsinghua Life Sciences Joint Center, Peking University Institute of Frontier Interdisciplinary Studies, Beijing 100871, China

Corresponding author: WANG G H, E-mail: wanggaohua64@126.com

Conflicts of interest   None.

ACKNOWLEDGMENTS National Natural Science Foundation of China (No. 82071523).
Received  2023-05-04
Accepted  2023-11-24
DOI: 10.12015/issn.1674-8034.2023.12.019
Cite this article as: GAO Y J, SUN J, GUO X, et al. Research progress of resting-state functional magnetic resonance imaging in the auxiliary diagnosis and early prognosis of bipolar disorder[J]. Chin J Magn Reson Imaging, 2023, 14(12): 111-115. DOI:10.12015/issn.1674-8034.2023.12.019.

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