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Application and research progress of MR perfusion imaging in small cerebral vascular disease
LIU Dan  WANG Tao  WEI Mei  CAI Jiyong 

Cite this article as: LIU D, WANG T, WEI M, et al. Application and research progress of MR perfusion imaging in small cerebral vascular disease[J]. Chin J Magn Reson Imaging, 2023, 14(12): 136-140. DOI:10.12015/issn.1674-8034.2023.12.024.


[Abstract] Cerebral small vessel disease (CSVD), a common cause of stroke and dementia, is a dynamic whole-brain dysfunction disease caused by the abnormity of the neurovascular unit. Chronic cerebral ischemia and hypoperfusion, endothelial dysfunction and blood-brain barrier (BBB) disruption are considered to be important pathogenic mechanisms. Magnetic resonance perfusion imaging technology can provide multi-parameter about perfusion information, observe the changes of BBB permeability and vascular reactivity, so that CSVD can be diagnosed earlier, the technology can also give opportunity to early reversal, and provide technical support for the verification of potential protective drug intervention. In this article, we reviewed the application and research progress of three different magnetic resonance perfusion imaging techniques in CSVD.
[Keywords] cerebral small vessel disease；magnetic resonance imaging；magnetic resonance perfusion imaging；dynamic susceptibility contrast imaging；dynamic contrast enhanced imaging；arterial spin labeling

LIU Dan   WANG Tao*   WEI Mei   CAI Jiyong  

Department of Radiology, Bishan Hospital Affiliated to Chongqing Medical University (Chongqing Bishan District People's Hospital), Chongqing 402760, China

Corresponding author: WANG T, E-mail: phrade@126.com

Conflicts of interest   None.

ACKNOWLEDGMENTS Chongqing Science and Health Joint Medical Research Program Youth Program (No. 2022QNXM041).
Received  2023-05-14
Accepted  2023-11-06
DOI: 10.12015/issn.1674-8034.2023.12.024
Cite this article as: LIU D, WANG T, WEI M, et al. Application and research progress of MR perfusion imaging in small cerebral vascular disease[J]. Chin J Magn Reson Imaging, 2023, 14(12): 136-140. DOI:10.12015/issn.1674-8034.2023.12.024.

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