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• Clinical Article •
Study of diffusion tensor imaging parameters in foraminal cervical nerve of healthy volunteers and fiber bundle reconstruction
LI Bingxuan  SHI Yin  DING Hongyuan  ZOU Yuefen 

Cite this article as: LI B X, SHI Y, DING H Y, et al. Study of diffusion tensor imaging parameters in foraminal cervical nerve of healthy volunteers and fiber bundle reconstruction[J]. Chin J Magn Reson Imaging, 2024, 15(1): 101-105, 124. DOI:10.12015/issn.1674-8034.2024.01.016.


[Abstract] Objective To observe the intervertebral foramen segments of cervical nerve roots by diffusion tensor tractography (DTT) and quantitatively analyze diffusion tensor imaging (DTI) parameters of healthy volunteers, to provide the reference for clinical diagnosis and treatment of cervical spondylotic radiculopathy.Materials and Methods DTI and DTT of the cervical nerve roots were performed in fifty healthy volunteers (25 males and 25 females). Mean fractional anisotropy (FA) and ADC values of the cervical nerve roots (both sides of cervical nerve roots C5 to C7, proximal,middle and distal to the cervical foraminal zone) were obtained.Differences among various segments of cervical nerve roots were compared with ANOVA test; Differences between two sides of the cervical nerve roots at the same cervical segment were compared with paired samples t-test; Differences between the proximal, middle and distal nerve to the cervical foraminal zone at the same cervical segment were compared with the LSD test. Nerve fiber bundle reconstruction was performed on the both sides of cervical nerve roots C5 to C7.Results There was no significant difference in FA and ADC values among the proximal, middle and distal nerve to the cervical foraminal zone in different segments of C5 to C7. There was no significant difference in FA and ADC values between the left and right sides of the nerve roots at the same cervical segment. The difference in FA and ADC values between the nerve roots at three different levels of the same segment of C5 to C7 was significant (P<0.05). The whole length of the cervical nerve roots C5 to C7 could be visualized clearly by using DTT.Conclusions DTI and DTT can quantitatively evaluate the cervical nerve roots in the cervical foraminal segment and visually reconstruct the cervical nerve bundles, and can provide quantitative parameters and visual reconstruction images of cervical nerve roots in the proximal, middle and distal segments of the intervertebral foramina for the diagnosis of cervical spondylotic radiculopathy.
[Keywords] diffusion tensor imaging；diffusion tensor tractography；intervertebral foramen；cervical nerve roots；magnetic resonance imaging

LI Bingxuan   SHI Yin   DING Hongyuan   ZOU Yuefen*  

Department of Radiology, the First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China

Corresponding author: ZOU Y F, E-mail: zouyuefendc@126.com

Conflicts of interest   None.

Received  2023-05-29
Accepted  2023-12-04
DOI: 10.12015/issn.1674-8034.2024.01.016
Cite this article as: LI B X, SHI Y, DING H Y, et al. Study of diffusion tensor imaging parameters in foraminal cervical nerve of healthy volunteers and fiber bundle reconstruction[J]. Chin J Magn Reson Imaging, 2024, 15(1): 101-105, 124. DOI:10.12015/issn.1674-8034.2024.01.016.

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