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Advances in functional MRI in cognitive impairment of moyamoya disease
FU Lin  YU Hao  LIU Deguo 

Cite this article as: FU L, YU H, LIU D G. Advances in functional MRI in cognitive impairment of moyamoya disease[J]. Chin J Magn Reson Imaging, 2024, 15(1): 189-193. DOI:10.12015/issn.1674-8034.2024.01.032.


[Abstract] Moyamoya disease (MMD) is a progressive stenotic or occlusive cerebrovascular disease of unknown etiology, and cognitive impairment is one of the more common accompanying symptoms. Functional magnetic resonance imaging (fMRI) can noninvasively evaluate the cerebral hemodynamics, brain microstructure, and brain functional networks of MMD patients, and reveal the pathophysiological mechanisms of cognitive impairment in MMD patients from different perspectives. This article reviews the technical principles of perfusion weighted imaging (PWI), diffusion tensor imaging (DTI), neurite orientation dispersion and density imaging (NODDI), and blood oxygenation level dependent fMRI (BOLD-fMRI) and their application in MMD cognitive impairment. In order to provide a reference direction for the further study of the pathophysiological mechanism of MMD cognitive impairment, and lay a theoretical foundation for the early diagnosis, treatment and evaluation of MMD cognitive impairment.
[Keywords] moyamoya disease；functional magnetic resonance imaging；magnetic resonance imaging；cognitive impairment

FU Lin1   YU Hao2   LIU Deguo2*  

1 Clinical School, Jining Medical University, Jining 272013, China

2 Department of Medical Imaging, Affiliated Hospital of Jining Medical University, Jining 272029, China

Corresponding author: LIU D G, E-mail: sdjnliudeguo@163.com

Conflicts of interest   None.

Received  2023-09-12
Accepted  2024-01-05
DOI: 10.12015/issn.1674-8034.2024.01.032
Cite this article as: FU L, YU H, LIU D G. Advances in functional MRI in cognitive impairment of moyamoya disease[J]. Chin J Magn Reson Imaging, 2024, 15(1): 189-193. DOI:10.12015/issn.1674-8034.2024.01.032.

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