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Advances in diffusion magnetic resonance imaging of cerebral white matter and cognitive impairment in patients with obstructive sleep apnoea
ZHOU Tianyu  ZHU Xiaoying  ZHANG Qing 

Cite this article as: ZHOU T Y, ZHU X Y, ZHANG Q. Advances in diffusion magnetic resonance imaging of cerebral white matter and cognitive impairment in patients with obstructive sleep apnoea[J]. Chin J Magn Reson Imaging, 2024, 15(1): 199-204, 228. DOI:10.12015/issn.1674-8034.2024.01.034.


[Abstract] Obstructive sleep apnoea (OSA) is a worldwide sleep-disordered breathing condition featuring intermittent hypoxaemia, hypercapnia, microarousals, and sleep fragmentation. This results in structural and functional alterations within the brain. Many studies have demonstrated that OSA is a significant contributor to cognitive impairment. Diffusion magnetic resonance imaging (dMRI) measures water molecule diffusion properties in tissues to obtain detailed information about tissue microstructures. It is highly sensitive and specific in detecting pathological changes in tissue microstructures, particularly in the diagnosis of white matter fibrotic lesions. In recent years, dMRI has rapidly emerged and become widely used in the study of cerebral white matter and cognitive impairment associated with OSA. This paper examines dMRI studies on cerebral white matter and cognitive function in individuals with OSA. We analyze changes in cerebral white matter diffusion parameters in OSA patients across multiple sequences and explore the relationship between neuropathological changes and cognitive impairment in OSA. Our findings provide a neuroimaging basis for diagnosing cognitive impairment in individuals with OSA.
[Keywords] obstructive sleep apnea；diffusion magnetic resonance imaging；magnetic resonance imaging；cognitive impairment；white matter of brain

ZHOU Tianyu   ZHU Xiaoying   ZHANG Qing*  

Department of Radiology, Zhongshan Hospital Affiliated to Dalian University, Dalian 116001, China

Corresponding author: ZHANG Q, E-mail: zhangqingsmile@163.com

Conflicts of interest   None.

Received  2023-10-26
Accepted  2023-12-05
DOI: 10.12015/issn.1674-8034.2024.01.034
Cite this article as: ZHOU T Y, ZHU X Y, ZHANG Q. Advances in diffusion magnetic resonance imaging of cerebral white matter and cognitive impairment in patients with obstructive sleep apnoea[J]. Chin J Magn Reson Imaging, 2024, 15(1): 199-204, 228. DOI:10.12015/issn.1674-8034.2024.01.034.

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