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• Clinical Article •
The correlation between symptomatic carotid atherosclerotic plaques and short-term mRS score after ischemic stroke
WU Jingjing  ZHANG Yating  ZHANG Lin  YIN Xi  SONG Juan  WANG Chengwei 

Cite this article as: WU J J, ZHANG Y T, ZHANG L, et al. The correlation between symptomatic carotid atherosclerotic plaques and short-term mRS score after ischemic stroke[J]. Chin J Magn Reson Imaging, 2024, 15(3): 26-30. DOI:10.12015/issn.1674-8034.2024.03.005.


[Abstract] Objective High resolution magnetic resonance vessel wall imaging (HR-VWI) was used to analyze the correlation between the composition of symptomatic carotid atherosclerotic plaque and the mRS score three months after secondary prevention of stroke in patients with first ischemic stroke, so as to provide a theoretical basis for the prognosis evaluation of such patients.Materials and Methods From November 2022 to June 2023, patients with ischemic stroke symptoms and carotid atherosclerotic plaque on the symptomatic side were recruited in the First Affiliated Hospital of Shihezi University. Patients who meet the inclusion and exclusion criteria and have completed secondary stroke prevention for 3 months will be continuously enrolled in this study and will receive a modified Rankin Scale (mRS) score. Based on the mRS score, the enrolled patients will be divided into a poor prognosis group (mRS≥2) and a good prognosis group (mRS<2). Compare the clinical data, plaque composition on the first HR-VWI examination, and plaque composition three months after secondary stroke prevention between two groups of patients. Analyzing the correlation between different components in plaques and mRS scores.Results A total of 66 patients were included in the group (39 in the poor prognosis group and 27 in the good prognosis group), and there was no statistically significant difference in clinical data between the two groups (P>0.05). In the first examination, the proportion of plaque bleeding in the poor prognosis group was higher than that in the good prognosis group (P<0.05), and the proportion and volume of calcification in plaques in the good prognosis group were higher than those in the poor prognosis group (P<0.05); After 3 months of secondary prevention of stroke, there was no significant difference in the proportion of plaque bleeding between the poor prognosis group and the good prognosis group (P>0.05), while the good prognosis group had a larger proportion and volume of calcification in plaques (P<0.05).Conclusions The calcification and calcification volume in symptomatic carotid atherosclerotic plaques were correlated with the mRS score 3 months after secondary prevention of stroke in patients with first ischemic stroke; HR-VWI at the initial stage of symptoms can provide a theoretical basis for the prognosis evaluation of ischemic stroke patients due to carotid atherosclerotic plaque.
[Keywords] carotid atherosclerotic plaque；ischemic stroke；modified Rankin Scale；high-resolution magnetic resonance vessel wall imaging；magnetic resonance imaging

WU Jingjing   ZHANG Yating   ZHANG Lin   YIN Xi   SONG Juan   WANG Chengwei*  

Department of Magnetic Resonance, the First Affiliated Hospital of Shihezi University, Shihezi 832000, China

Corresponding author: WANG C W, E-mail: 308199733@qq.com

Conflicts of interest   None.

Received  2023-09-09
Accepted  2024-02-05
DOI: 10.12015/issn.1674-8034.2024.03.005
Cite this article as: WU J J, ZHANG Y T, ZHANG L, et al. The correlation between symptomatic carotid atherosclerotic plaques and short-term mRS score after ischemic stroke[J]. Chin J Magn Reson Imaging, 2024, 15(3): 26-30. DOI:10.12015/issn.1674-8034.2024.03.005.

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