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• Technical Article •
Value in EH diagnosis of PPI and HYDROPS of 3D CUBE FLAIR based on inner ear magnetic resonace imaing with gadolinium enhancement
WANG Zikun  FENG Jingjing  WU Jie  YE Yufang  CHEN Yingmin  SHI Yuan  WU Jing  SUN Liqiang 

Cite this article as: WANG Z K, FENG J J, WU J, et al. Value in EH diagnosis of PPI and HYDROPS of 3D CUBE FLAIR based on inner ear magnetic resonace imaing with gadolinium enhancement[J]. Chin J Magn Reson Imaging, 2024, 15(3): 151-157, 176. DOI:10.12015/issn.1674-8034.2024.03.024.


[Abstract] Objective To assess the value in endolymphatic hydrops (EH) diagnosis of positive perilymph image (PPI) and HYDROPS (HYbriD of reversed image of positive endolymph signal and native image of positive perilymph signal) of three-dimensional fluid attenuated inversion recovery with CUBE (3D CUBE FLAIR) based on inner ear magnetic resonance imaging with contrast enhancement following intravenous injection of gadolinium.Materials and Methods The data and MRI images of 22 patients with EH on the affected side and without EH on the contralateral side were retrospectively analyzed. The Image J software was used to delineate the regions of interest the images obtained to analyze the signal intensity ratios (SIR) of the cochlear basal turn to the same side cerebellar white matter on affected and unaffected sides in the same image and SIRs of perilymph to the same side endolymph of vestibule both in PPI and HYDROPS; Count the numbers of cochlear EH on the affected side and the scores of vestibular EH boundaries definition both in PPI and HYDROPS. Evaluate the visualization of permeability change of the blood-labyrinth barrier (BLB) on the affected side, the vestibular developing effect, the cochlear EH sensibility and the development in vestibular EH boundaries in the two kinds of images.Results There was statistical difference in SIRs of the cochlear basal turn to the same side cerebellar white matter between affected and unaffected sides in PPI (P<0.001). There was statistical difference in SIRs of the cochlear basal turn to the same side cerebellar white matter between affected and unaffected sides in HYDROPS (P<0.001). There was statistical difference in SIRs of perilymph to the same side endolymph of vestibule between PPI and HYDROPS on the affected side (P<0.001). There was statistical difference in SIRs of perilymph to the same side endolymph of vestibule between PPI and HYDROPS on the unaffected side (P<0.001). There was statistical difference in the sensibility of the cochlear EH diagnosis between PPI and HYDROPS (P=0.030). There was statistical difference in the scores of vestibular EH boundaries definition between PPI and HYDROPS (P<0.001).Conclusions Combining PPI with HYDROPS in 3D CUBE FLAIR of inner ear gadolinium enhancing magnetic resonance imaging contributes to assessing the permeability, locating the EH and displaying the boundaries.
[Keywords] endolymphatic hydrops；cochlea；vestibule；blood-labyrinth barrier；permeability；gadolinium contrast agent；signal intensity ratio；magnetic resonance imaging

WANG Zikun1, 2   FENG Jingjing1, 2   WU Jie2   YE Yufang2*   CHEN Yingmin2   SHI Yuan2   WU Jing2   SUN Liqiang2  

1 Graduate School, Hebei North University, Zhangjiakou 075000, China

2 Medical Imaging Center, Hebei Provincial People's Hospital, Shijiazhuang 050051, China

Corresponding author: YE Y F, E-mail: 1301620722@qq.com

Conflicts of interest   None.

Received  2023-06-24
Accepted  2024-02-26
DOI: 10.12015/issn.1674-8034.2024.03.024
Cite this article as: WANG Z K, FENG J J, WU J, et al. Value in EH diagnosis of PPI and HYDROPS of 3D CUBE FLAIR based on inner ear magnetic resonace imaing with gadolinium enhancement[J]. Chin J Magn Reson Imaging, 2024, 15(3): 151-157, 176. DOI:10.12015/issn.1674-8034.2024.03.024.

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