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Progress in imaging research on the blood-brain barrier associated with Alzheimer's disease
WANG Bingbing  LUO Yu  BAI Yan  WU Yaping  SHEN Yu  WANG Meiyun 

Cite this article as: WANG B B, LUO Y, BAI Y, et al. Progress in imaging research on the blood-brain barrier associated with Alzheimer's disease[J]. Chin J Magn Reson Imaging, 2024, 15(4): 192-196. DOI:10.12015/issn.1674-8034.2024.04.032.


[Abstract] Alzheimer's disease (AD) is the most common cause of dementia in the elderly people, and its pathogenesis remains unclear. Research has found that blood-brain barrier (BBB) injury is tightly associated with AD pathology and plays a crucial role in the pathogenesis and progression of AD. Imaging technology is an effective method for exploring changes in the structure and function of BBB. This article will summarize the internal relationship between BBB injury and AD pathology and the current application status of imaging technology in it, in order to provide new ideas for the early diagnosis and treatment of AD.
[Keywords] Alzheimer's disease；blood-brain barrier；magnetic resonance imaging；positron emission tomography；magnetic resonance-guided focused ultrasound

WANG Bingbing1, 2   LUO Yu1, 2   BAI Yan2   WU Yaping2   SHEN Yu2   WANG Meiyun1, 2*  

1 Department of Medical Imaging, Henan Provincial People's Hospital & Zhengzhou University People's Hospital, Zhengzhou 450003, China

2 Department of Medical Imaging, Henan Provincial People's Hospital, Zhengzhou 450003, China

Corresponding author: WANG M Y, E-mail: mywang@zzu.edu.cn

Conflicts of interest   None.

Received  2023-09-24
Accepted  2024-03-15
DOI: 10.12015/issn.1674-8034.2024.04.032
Cite this article as: WANG B B, LUO Y, BAI Y, et al. Progress in imaging research on the blood-brain barrier associated with Alzheimer's disease[J]. Chin J Magn Reson Imaging, 2024, 15(4): 192-196. DOI:10.12015/issn.1674-8034.2024.04.032.

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