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Progress in multimodal MRI research on acupuncture at Siguan point for the treatment of mild cognitive impairment
HAN Shengwang  LI Xiaoling  WANG Yang  HOU Yu  WEI Zeyi  GAO Shenglan  WANG Long 

Cite this article as: HAN S W, LI X L, WANG Y, et al. Progress in multimodal MRI research on acupuncture at Siguan point for the treatment of mild cognitive impairment[J]. Chin J Magn Reson Imaging, 2024, 15(6): 138-143. DOI:10.12015/issn.1674-8034.2024.06.021.


[Abstract] Mild cognitive impairment (MCI) is the early stage of Alzheimer's disease (AD), characterized by decreased learning and memory abilities, with no impact on daily life. Acupuncture at Siguan point has a definite therapeutic effect on MCI and is widely used in clinical practice; acupuncture can improve cognitive function, but the principle of action is complex. Multimodal MRI provides visual support for the study of brain effects and efficacy assessment of acupuncture at the Siguan point in the treatment of MCI due to its advantages of precise localization and real-time observation of abnormal brain regions.In this article, structural MRI (sMRI), diffusion tensor imaging (DTI), blood oxygen level dependent functional magnetic resonance imaging (BOLD-fMRI), magnetic resonance spectroscopy (MRS), and arterial spin labeling (ASL) were introduced to review the literature on cerebral structure, function, metabolism and blood perfusion of MCI treated by acupuncture at Siguan point. The intracerebral changes of MCI were discussed from multiple perspectives and the mechanism of acupuncture treatment was analyzed, it provides new ideas for the follow-up research of MCI.
[Keywords] Alzheimer's disease；mild cognitive impairment；acupuncture at Siguan point；magnetic resonance imaging；structural magnetic resonance imaging；functional magnetic resonance imaging；diffusion tensor imaging；magnetic resonance spectroscopy；arterial spin labeling

HAN Shengwang1, 2   LI Xiaoling3   WANG Yang3#   HOU Yu4   WEI Zeyi2   GAO Shenglan2   WANG Long5*  

1 The Third Department of Rehabilitation, the Second Affiliated Hospital of Heilongjiang University of Traditional Chinese Medicine, Harbin 150001, China

2 Graduate School of Heilongjiang University of Traditional Chinese Medicine, Harbin 150040, China

3 Department of CT & MR, the First Affiliated Hospital of Heilongjiang University of Traditional Chinese Medicine, Harbin 150040, China

4 Department of Gynecology, Harbin Hospital of Traditional Chinese Medicine, Harbin 150020, China

5 The Third Department of Acupuncture and Moxibustion, the First Hospital Affiliated to Heilongjiang University of Chinese Medicine, Harbin 150040, China

Corresponding author: WANG L, E-mail: wlkeyan@163.com

Conflicts of interest   None.

Received  2024-02-04
Accepted  2024-06-06
DOI: 10.12015/issn.1674-8034.2024.06.021
Cite this article as: HAN S W, LI X L, WANG Y, et al. Progress in multimodal MRI research on acupuncture at Siguan point for the treatment of mild cognitive impairment[J]. Chin J Magn Reson Imaging, 2024, 15(6): 138-143. DOI:10.12015/issn.1674-8034.2024.06.021.

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