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• Review •
Research progress of CT and MRI with radiomics to predict microsatellite instability in colorectal cancer
PENG Leping  ZHANG Xiuling  SHI Liuyan  HUANG Gang  MA Yaqiong  AI Kai  WANG Lili  MA Wenting  MA Xiaomei 

Cite this article as: PENG L P, ZHANG X L, SHI L Y, et al. Research progress of CT and MRI with radiomics to predict microsatellite instability in colorectal cancer[J]. Chin J Magn Reson Imaging, 2024, 15(6): 218-223. DOI:10.12015/issn.1674-8034.2024.06.035.


[Abstract] Colorectal cancer is a common malignant tumor of the digestive tract with high mortality, and its pathogenesis is closely related to the genetic changes of tumor cells. Microsatellite instability (MSI) is a common genetic change that causes colorectal development and plays a crucial role in the development and progression of tumors and in the treatment and prognosis of patients. In recent years, medical imaging methods with the advantages of non-invasiveness and individualization have begun to make initial progress in evaluating high MSI (MSI-H) status in colorectal cancer. With the continuous optimization of software technology and the rise of artificial intelligence, computed tomography (CT) and MRI with radiomics methods have become increasingly important in the preoperative prediction, treatment, efficacy monitoring, and prognosis assessment of MSI-H status in colorectal cancer. This review aims to summarize the advantages and prospects of CT and MRI techniques and radiomics methods in predicting the MSI-H status of colorectal cancer, to provide more accurate and non-invasive MSI prediction methods for clinical practice, and provide new ideas for the selection of treatment measures for colorectal cancer patients.
[Keywords] colorectal cancer；high microsatellite instability；computed tomography；magnetic resonance imaging；radiomics

PENG Leping1   ZHANG Xiuling1   SHI Liuyan1   HUANG Gang3   MA Yaqiong3   AI Kai2   WANG Lili3*   MA Wenting3   MA Xiaomei3  

1 The First Clinical College of Medicine, Gansu University of Chinese Medicine, Lanzhou 730000,China

2 Philips (China) Investment Co. LTD, Shanghai 200040, China

3 Department of Radiology, Gansu Provincial People's Hospital, Lanzhou 730000,China

Corresponding author: WANG L L, E-mail: Wanglilihq@163.com

Conflicts of interest   None.

Received  2024-03-01
Accepted  2024-06-03
DOI: 10.12015/issn.1674-8034.2024.06.035
Cite this article as: PENG L P, ZHANG X L, SHI L Y, et al. Research progress of CT and MRI with radiomics to predict microsatellite instability in colorectal cancer[J]. Chin J Magn Reson Imaging, 2024, 15(6): 218-223. DOI:10.12015/issn.1674-8034.2024.06.035.

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