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Principles and clinical advances of magnetic resonance spin lock imaging
HE Siyi  LI Bowei  CHENG Guanxun 

Cite this article as: HE S Y, LI B W, CHENG G X. Principles and clinical advances of magnetic resonance spin lock imaging[J]. Chin J Magn Reson Imaging, 2024, 15(6): 229-234. DOI:10.12015/issn.1674-8034.2024.06.037.


[Abstract] Magnetic resonance spin-locked imaging (T1ρ imaging) can detect changes in tissue metabolism and biochemical information at the molecular level, the T1ρ value is more sensitive than the T1 and T2 values to reflect the low-frequency movement between water molecules and macromolecules. In recent years, researchers have continuously improved this sequence and gradually applied it to a variety of diseases including osteoarthritis, intervertebral disc degeneration, cardiomyopathy, liver fibrosis, renal fibrosis, Alzheimer's disease, multiple sclerosis, and brain gliomas. This article will review the principles of T1ρ imaging, factors influencing T1ρ values, and the current research status of clinical applications of T1ρ imaging, aiming to promote the continuous maturity of T1ρ technology and assist in guiding clinical diagnosis and treatment.
[Keywords] osteoarthritis；cardiomyopathy；liver fibrosis；spin-lock imaging；magnetic resonance imaging

HE Siyi1, 2   LI Bowei1   CHENG Guanxun1*  

1 Department of Medical Imaging, Peking University Shenzhen Hospital, Shenzhen 518000, China

2 Peking University Health Science Center, Beijing 100191, China

Corresponding author: CHENG G X, E-mail: 18903015678@189.cn

Conflicts of interest   None.

Received  2024-03-15
Accepted  2024-05-31
DOI: 10.12015/issn.1674-8034.2024.06.037
Cite this article as: HE S Y, LI B W, CHENG G X. Principles and clinical advances of magnetic resonance spin lock imaging[J]. Chin J Magn Reson Imaging, 2024, 15(6): 229-234. DOI:10.12015/issn.1674-8034.2024.06.037.

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