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• Clinical Article •
Exploring the cut-off age value of marrow transformation in children's clivus by MRI
TANG Qiongmei  HUANG Qinpeng  HU Shiteng 

Cite this article as: TANG Q M, HUANG Q P, HU S T. Exploring the cut-off age value of marrow transformation in children's clivus by MRI[J]. Chin J Magn Reson Imaging, 2024, 15(8): 97-102. DOI:10.12015/issn.1674-8034.2024.08.015.


[Abstract] Objective To analyze the characteristics of MRI of normal slopes in children, and to explore the cut-off age value for the onset of marrow transformation of the clivus in children, so as to better identify myelopathy.Materials and Methods The children who underwent cerebral magnetic resonance examination in the Department of Radiology of our hospital from April 2022 to October 2023 were selected as the research objects. By analyzing the relationship between the characteristics of normal clivus's signal and age distribution in 2141 children, the age standard of the beginning of marrow transformation in children's clivus was explored. The signal characteristics of the clivus were observed on the median sagittal plane of the craniocerebral MRI T1WI sequence, and the age distribution characteristics of non-transformation and transformation were analyzed. Youden index was calculated and the receiver-operating chatacteristic (ROC) curve was drawn to explore the cut-off age value of the beginning of marrow transformation in children's clivus.Results Among the 2141 children, 1339 were boys and 802 were girls. Among 1339 boys, 521 boys (1 month-36 months) had clivus with non-transformated marrow and 818 boys (4 months-180 monts) had clivus with transformated marrow. Among the 802 girls, 326 girls (1 month-35 months) had clivus with non-transformated marrow and 476 girls (5 months-201 months) had clivus with transformated marrow. When the boy was 13.5 months old, the Youden index was the highest (0.814), and the area under ROC curve was the largest [0.976 (95% CI: 0.969-0.982)]. When the girl was 11.5 months old, the Youden index was 0.836 and the area under the ROC curve was 0.980 (95% CI: 0.973-0.987).Conclusions The age of boys >13.5 months can be regarded as the cut-off age value of marrow transformation of the clivus. The age of girls was >11.5 months, which could be used as the cut-off age value of marrow transformation of the clivus. Marrow transformation begins later in boys than in girls.
[Keywords] children；clivus；marrow transformation；magnetic resonance imaging；cut-off age value

TANG Qiongmei   HUANG Qinpeng   HU Shiteng*  

Department of Radiology, Chenzhou First People's Hospital, Chenzhou 423000, China

Corresponding author: HU S T, E-mail: hst0793@163.com

Conflicts of interest   None.

Received  2024-03-29
Accepted  2024-08-08
DOI: 10.12015/issn.1674-8034.2024.08.015
Cite this article as: TANG Q M, HUANG Q P, HU S T. Exploring the cut-off age value of marrow transformation in children's clivus by MRI[J]. Chin J Magn Reson Imaging, 2024, 15(8): 97-102. DOI:10.12015/issn.1674-8034.2024.08.015.

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