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Research progress in evaluating brain function of related brain regions in patients with insomnia disorder based on fMRI
CHEN Keke  WU Xiaoling  LI Zhonglin  ZOU Zhi  GU Yu'ang  JIA Shulei  ZHANG Xueyi  ZHANG Miao  LI Hao  YANG Ling  LI Yongli 

Cite this article as: CHEN K K, WU X L, LI Z L, et al. Research progress in evaluating brain function of related brain regions in patients with insomnia disorder based on fMRI[J]. Chin J Magn Reson Imaging, 2024, 15(8): 184-188, 206. DOI:10.12015/issn.1674-8034.2024.08.029.


[Abstract] Insomnia disorder (ID) is a sleep disorder that seriously affects the quality of life, long-term insomnia can lead to daytime dysfunction and depression, anxiety and other mental diseases, but also increase the risk of obesity, type 2 diabetes and cardiovascular disease, ID has become a major public health problem affecting the health of citizens. Functional magnetic resonance imaging (fMRI), as a non-invasive examination means, can reflect the physiological or pathological function of the brain, which is of great significance for the study of the pathogenesis of diseases, and plays an important role in the functional evaluation of brain regions in patients with ID. Studies have shown that patients with ID have functional abnormalities in several brain regions such as the amygdala, hippocampus and frontal lobe. Through fMRI technology, researchers can observe the changes in neuronal activity in these brain regions in patients with ID. The purpose of this paper is to review the recent research progress on the assessment of brain function in relevant brain regions of patients with ID using fMRI analysis, in order to provide a solid theoretical basis and imaging evidence for further exploration of the neuropathological mechanism of ID.
[Keywords] insomnia disorder；functional magnetic resonance imaging；magnetic resonance imaging；relevant brain areas；brain function

CHEN Keke1   WU Xiaoling2   LI Zhonglin3   ZOU Zhi3   GU Yu'ang1   JIA Shulei1   ZHANG Xueyi3   ZHANG Miao3   LI Hao4   YANG Ling5   LI Yongli6*  

1 Department of Medical Imaging, Xinxiang Medical College/Henan Provincial People's Hospital, Xinxiang 453003, China

2 Department of Nuclear Medicine, Henan Provincial People's Hospital/Zhengzhou University People's Hospital, Zhengzhou 450003, China

3 Department of Medical Imaging, People's Hospital of Zhengzhou University/Henan Provincial People's Hospital, Zhengzhou 450003, China

4 Department of Health Management, Fuwai Center China Cardiovascular Hospital, Zhengzhou 451460, China

5 Hebei Yiran Biotechnology Co., Ltd., Shijiazhuang 050800, China

6 Department of Health Management, Henan Provincial People's Hospital, Zhengzhou 450003, China

Corresponding author: LI Y L, E-mail: shyliyongli@126.com

Conflicts of interest   None.

Received  2024-04-17
Accepted  2024-08-02
DOI: 10.12015/issn.1674-8034.2024.08.029
Cite this article as: CHEN K K, WU X L, LI Z L, et al. Research progress in evaluating brain function of related brain regions in patients with insomnia disorder based on fMRI[J]. Chin J Magn Reson Imaging, 2024, 15(8): 184-188, 206. DOI:10.12015/issn.1674-8034.2024.08.029.

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