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Research progress on structural and functional changes of the amygdala in patients with insomnia using magnetic resonance imaging
JIA Shulei  SUN Yongbing  ZHOU Jing  WU Xiaoling  LI Zhonglin  LI Hao  ZOU Zhi  SHANG Feifei  LI Yongli 

Cite this article as: JIA S L, SUN Y B, WU X L, et al. Research progress on structural and functional changes of the amygdala in patients with insomnia using magnetic resonance imaging[J]. Chin J Magn Reson Imaging, 2024, 15(9): 135-139. DOI:10.12015/issn.1674-8034.2024.09.023.


[Abstract] Insomnia disorder (ID) constitutes a social public health concern and represents the second most prevalent type of mental illness globally. Furthermore, other mental disorders and physical ailments interact causally and mutually reinforce each other. The amygdala serves as a crucial emotional hub, not only regulating behavioral cognition and emotions but also functioning as a significant sleep regulator. With the progress of neuroimaging and MRI technology, it becomes feasible to illuminate the neuropathological mechanism of ID by analyzing the variations in the structure, function, fiber tracts and blood flow of the amygdala among ID patients. In this paper, the alterations in the amygdala of ID patients were summarized via MRI multimodal technology, with the aim of offering novel perspectives for the study of the pathological mechanism of ID and a fresh direction for treatment.
[Keywords] insomnia disorder；magnetic resonance imaging；resting state functional magnetic resonance imaging；real time functional magnetic resonance imaging with neural feedback；diffusion tensor imaging；amygdala；brain function

JIA Shulei1   SUN Yongbing2   ZHOU Jing3   WU Xiaoling4   LI Zhonglin2   LI Hao5   ZOU Zhi2   SHANG Feifei3   LI Yongli3*  

1 Xinxiang Medical University/Department of Medical Imaging, Henan Provincial People's Hospital, Xinxiang 453003, China

2 Department of Medical Imaging, Zhengzhou University People's Hospital/Henan Provincial People's Hospital, Zhengzhou 450003, China

3 Department of Health Management, Henan Proincial People's Hospital, Zhengzhou 450003, China

4 Department of Nuclear Medicine, Henan Proincial People's Hospital/Zhengzhou University People's Hospital,Zhengzhou 450003, China

5 Department of Health Management, Fuwai Huazhong Cardiovascular Hospital, Zhengzhou 451450, China

Corresponding author: LI Y L, E-mail: shyliyongli@126.com

Conflicts of interest   None.

Received  2024-04-07
Accepted  2024-09-10
DOI: 10.12015/issn.1674-8034.2024.09.023
Cite this article as: JIA S L, SUN Y B, WU X L, et al. Research progress on structural and functional changes of the amygdala in patients with insomnia using magnetic resonance imaging[J]. Chin J Magn Reson Imaging, 2024, 15(9): 135-139. DOI:10.12015/issn.1674-8034.2024.09.023.

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