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Advancements in the application of 7 T-MRI in cerebral small vessel disease
HUANG Peiyu  LIU Chen  ZHEN Zhiming  ZHANG Ruiting 

Cite this article as: HUANG P Y, LIU C, ZHEN Z M, et al. Advancements in the application of 7 T-MRI in cerebral small vessel disease[J]. Chin J Magn Reson Imaging, 2024, 15(9): 151-156. DOI:10.12015/issn.1674-8034.2024.09.026.


[Abstract] Cerebral small vessel disease has a high incidence rate among the elderly, significantly increasing the risk of stroke and dementia. To date, there are no effective clinical or fluid biomarkers for the disease, and its diagnosis heavily relies on MRI. However, due to the limited spatial resolution of clinical imaging, it's challenging to directly assess small vessel damage. Thus, researchers primarily use imaging biomarkers reflecting cerebral parenchymal damage to evaluate small vessel injury. In recent years, with the continuous maturation of ultra-high-field (7 T) MRI technology, its application in the field of cerebral small vessel disease has become increasingly extensive. 7 T-MRI can directly assess the structure and function of small cerebral vessels and significantly enhance the detection sensitivity of minor cerebral parenchymal lesions, providing important tools for the mechanism research and precise diagnosis of cerebral small vessel disease. This article will review the recent research on cerebral small vessel disease based on 7 T-MRI and discuss potential issues and future research directions, offering references for researchers in the field.
[Keywords] cerebral small vessel disease；magnetic resonance imaging；ultra-high field；time-of-flight magnetic resonance angiography；phase-contrast magnetic resonance angiography；susceptibility-weighted imaging

HUANG Peiyu1, 2*   LIU Chen1, 2   ZHEN Zhiming1, 2   ZHANG Ruiting1, 2  

1 Department of Radiology, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China

2 7 T Magnetic Resonance Translational Medicine Research Center, Department of Radiology, Southwest Hospital, Army Medical University (Third Military Medical University), Chongqing 400038, China

Corresponding author: HUANG P Y, E-mail: huangpy@zju.edu.cn

Conflicts of interest   None.

Received  2024-03-31
Accepted  2024-07-10
DOI: 10.12015/issn.1674-8034.2024.09.026
Cite this article as: HUANG P Y, LIU C, ZHEN Z M, et al. Advancements in the application of 7 T-MRI in cerebral small vessel disease[J]. Chin J Magn Reson Imaging, 2024, 15(9): 151-156. DOI:10.12015/issn.1674-8034.2024.09.026.

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