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Advances in magnetic resonance imaging research on cardiotoxicity of immune checkpoint inhibitors
LUO Shuying  YU Hong  LI Bangguo 

Cite this article as: LUO S Y, YU H, LI B G. Advances in magnetic resonance imaging research on cardiotoxicity of immune checkpoint inhibitors[J]. Chin J Magn Reson Imaging, 2024, 15(9): 172-177. DOI:10.12015/issn.1674-8034.2024.09.030.


[Abstract] Cardiotoxicity is a potential complication of immune checkpoint inhibitors (ICIs) in the treatment of malignant tumors. Although the incidence of ICIs-related cardiotoxicity is low, it can threaten the lives of patients. Cardiac magnetic resonance imaging (CMR) imaging has the advantages of better soft tissue resolution and multi-functional, multi-parameter imaging. Techniques such as cine sequences, late gadolinium enhancement (LGE), T1 mapping, T2 mapping, and feature tracking (FT) play a crucial role in the comprehensive assessment and early diagnosis of ICIs-related cardiotoxicity. This article summarizes the quantitative and qualitative analysis of ICIs-related cardiotoxicity through these techniques, and provides new methods and ideas for early clinical diagnosis of ICIs-related cardiotoxicity, so as to ensure the safety of patients during treatment, thereby improving the quality of life of patients, and is expected to provide reference direction for future research.
[Keywords] cardiac magnetic resonance；immune checkpoint inhibitors；cardiotoxicity；magnetic resonance imaging；T1 mapping；feature tracking

LUO Shuying   YU Hong   LI Bangguo*  

Department of Radiology, Affiliated Hospital of Zunyi Medical University, Medical Imaging Center of Guizhou Province, Zunyi 563003, China

Corresponding author: LI B G, E-mail: lbg2015@163.com

Conflicts of interest   None.

Received  2024-05-20
Accepted  2024-08-12
DOI: 10.12015/issn.1674-8034.2024.09.030
Cite this article as: LUO S Y, YU H, LI B G. Advances in magnetic resonance imaging research on cardiotoxicity of immune checkpoint inhibitors[J]. Chin J Magn Reson Imaging, 2024, 15(9): 172-177. DOI:10.12015/issn.1674-8034.2024.09.030.

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