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Research progress of brain MRI on the central thalamo-frontal-somatosensory cortex circuit in lifelong premature ejaculation
LI Qian  LU Jiaming  ZHU Zhengyang  LI Xin  ZHANG Wen  ZHANG Xin  ZHANG Bing 

Cite this article as: LI Q, LU J M, ZHU Z Y, et al. Research progress of brain MRI on the central thalamo-frontal-somatosensory cortex circuit in lifelong premature ejaculation[J]. Chin J Magn Reson Imaging, 2024, 15(10): 176-181, 186. DOI:10.12015/issn.1674-8034.2024.10.030.


[Abstract] Lifelong premature ejaculation (LPE) is the most common sexual dysfunction disorder in men, yet its central pathogenesis remains unclear. In recent years, researchers have employed multimodal magnetic resonance imaging (MRI) techniques to detect and analyze specific changes in the brain structure and function of LPE patients. Their focus has particularly been on the thalamo-frontal circuit related to the reward system and the somatosensory cortex involved in the ejaculation cycle. This article reviews the findings from brain MRI studies of LPE patients based on the thalamus-frontal-somatosensory cortex circuit. It aims to explore the role and mechanisms of the thalamus-frontal-somatosensory cortex circuit in the central nervous system of LPE, providing a scientific basis for developing new methods for the assessment and evaluation of premature ejaculation.
[Keywords] lifelong premature ejaculation；brain magnetic resonance imaging；resting-state functional magnetic resonance imaging；task-state functional magnetic resonance imaging；thalamus；frontal lobe；somatosensory cortex

LI Qian1   LU Jiaming2   ZHU Zhengyang2   LI Xin2   ZHANG Wen2   ZHANG Xin2   ZHANG Bing1, 2*  

1 Medical School of Nanjing University, Nanjing 210093, China

2 Department of Medical Imaging, the Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing 210008, China

Corresponding author: ZHANG B, E-mail: zhangbing_nanjing@nju.edu.cn

Conflicts of interest   None.

Received  2024-07-01
Accepted  2024-10-10
DOI: 10.12015/issn.1674-8034.2024.10.030
Cite this article as: LI Q, LU J M, ZHU Z Y, et al. Research progress of brain MRI on the central thalamo-frontal-somatosensory cortex circuit in lifelong premature ejaculation[J]. Chin J Magn Reson Imaging, 2024, 15(10): 176-181, 186. DOI:10.12015/issn.1674-8034.2024.10.030.

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